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免疫治疗的持续时间——我们应该无限期地持续下去吗?

Duration of immunotherapy - should we continue ad infinitum?

作者信息

Smith Annabel, Shaghayegh Gohar, Menzies Alexander M, Roberts-Thomson Rachel

机构信息

Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Department of Surgery, Basil Hetzel Institute for Translational Research, Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

出版信息

Intern Med J. 2020 Jul;50(7):865-868. doi: 10.1111/imj.14919.

Abstract

The optimal duration of immunotherapy treatment for cancer patients is unknown. As the survival data from early immunotherapy trials mature we are beginning to appreciate how durable responses can be post-discontinuation. The purpose of this brief communication is to comment on treatment duration of immunotherapy in patients with melanoma and non-small cell lung cancer and to provide practice guidance in support of discontinuation.

摘要

癌症患者免疫治疗的最佳疗程尚不清楚。随着早期免疫治疗试验生存数据的成熟,我们开始认识到停药后反应的持久程度。本简短通讯的目的是对黑色素瘤和非小细胞肺癌患者免疫治疗的疗程进行评论,并提供支持停药的实践指导。

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