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测量食管吻合口狭窄指数作为预测食管闭锁手术后扩张的指标。

Measuring esophageal anastomotic stricture index as a predictor of dilatation following esophageal atresia surgical repair.

机构信息

Pediatric Surgery Department. Gregorio Marañón University Hospital. Madrid (Spain).

出版信息

Cir Pediatr. 2020 Jul 1;33(3):119-124.

Abstract

INTRODUCTION

Anastomotic stricture is the most common complication following esophageal atresia (EA) surgical repair. The objective of this study was to evaluate Anastomotic Stricture Index (ASI: relationship between pouch and stricture diameters in the postoperative esophagram) as a predictor of the need for esophageal dilatation.

METHODS

A retrospective review of all patients undergoing EA repair in our healthcare facility from 2009 to 2017 was designed. Proximal pouch ASI (proximal ASI) and distal pouch ASI (distal ASI) in the first and second postoperative esophagram were calculated, and correlation with the number of esophageal dilatations required was studied. For statistical analysis purposes, Spearman's correlation test and ROC curves were used.

RESULTS

Of the 31 patients included, 21 (67.7%) required esophageal dilatation, and 11 (35.5%) required 3 or more dilatations. The relationship between ASIs in the first esophagram and the need for esophageal dilatation was not statistically significant (p >0.05). The relationship between proximal ASI (RHO = 0.84, p <0.05) and the number of dilatations in the second esophagram was statistically significant. None of the patients with <0.55 proximal ASI required dilatation; patients with 0.55-0.79 proximal ASI required less than 3 dilatations; and patients with >0.79 proximal ASI had a high risk of requiring 3 or more dilatations.

CONCLUSION

According to our study, measuring ASI in the second esophagram proves useful in predicting EA patients' postoperative management, especially when it comes to identifying patients with lower risk of undergoing multiple dilatations.

摘要

介绍

食管闭锁(EA)手术后吻合口狭窄是最常见的并发症。本研究的目的是评估吻合口狭窄指数(ASI:术后食管造影中吻合口和狭窄直径之间的关系)作为需要食管扩张的预测指标。

方法

设计了一项对 2009 年至 2017 年期间在我们医疗机构接受 EA 修复的所有患者进行的回顾性研究。计算了第一次和第二次术后食管造影中近端囊袋 ASI(近端 ASI)和远端囊袋 ASI(远端 ASI),并研究了与需要食管扩张的次数之间的相关性。为了进行统计分析,使用 Spearman 相关检验和 ROC 曲线。

结果

31 例患者中,21 例(67.7%)需要食管扩张,11 例(35.5%)需要 3 次或更多次扩张。第一次食管造影中 ASI 与需要食管扩张之间的关系无统计学意义(p>0.05)。近端 ASI(RHO=0.84,p<0.05)与第二次食管造影中扩张次数的关系具有统计学意义。近端 ASI<0.55 的患者无一例需要扩张;近端 ASI 为 0.55-0.79 的患者需要少于 3 次扩张;近端 ASI>0.79 的患者有需要 3 次或更多次扩张的高风险。

结论

根据我们的研究,测量第二次食管造影中的 ASI 有助于预测 EA 患者的术后管理,尤其是在确定需要多次扩张的患者的风险较低时。

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