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人血小板对曼氏血吸虫童虫的IgE依赖性杀伤作用:T细胞产物的调节

IgE-dependent killing of Schistosoma mansoni schistosomula by human platelets: modulation by T cell products.

作者信息

Pancré V, Cesbron J Y, Joseph M, Barbier M, Capron A, Auriault C

机构信息

Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Lille, France.

出版信息

Int Arch Allergy Appl Immunol. 1988;87(4):371-5. doi: 10.1159/000234703.

DOI:10.1159/000234703
PMID:3265932
Abstract

The in vitro stimulation of T lymphocytes is known to induce the release of factors that possess distinct biological activities. In the present report, we describe the presence, in supernatants of Schistosoma mansoni antigen stimulated T cells from S. mansoni infected patients, of a factor able to inhibit the IgE-dependent platelet cytotoxicity of the same individuals toward the young larvae of S. mansoni.

摘要

已知体外刺激T淋巴细胞可诱导具有不同生物活性的因子释放。在本报告中,我们描述了在曼氏血吸虫感染患者的曼氏血吸虫抗原刺激的T细胞上清液中,存在一种能够抑制同一个体针对曼氏血吸虫幼虫的IgE依赖性血小板细胞毒性的因子。

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1
IgE-dependent killing of Schistosoma mansoni schistosomula by human platelets: modulation by T cell products.人血小板对曼氏血吸虫童虫的IgE依赖性杀伤作用:T细胞产物的调节
Int Arch Allergy Appl Immunol. 1988;87(4):371-5. doi: 10.1159/000234703.
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A suppressive lymphokine of platelet cytotoxic functions.
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Functional analysis of a T cell line specific for antiidiotypic antibodies to a Schistosoma mansoni protective epitope. II. Induction of protective immunity in experimental rat schistosomiasis.针对曼氏血吸虫保护性表位的抗独特型抗体特异性T细胞系的功能分析。II. 实验性大鼠血吸虫病中保护性免疫的诱导
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引用本文的文献

1
Characterization of a suppressive factor of platelet cytotoxic functions in human and rat schistosomiasis mansoni.人和大鼠曼氏血吸虫病中血小板细胞毒性功能抑制因子的特性研究
Clin Exp Immunol. 1989 Jun;76(3):417-21.