Nakamura O, Matsutani M, Tanaka H, Ueki K, Nagashima T, Tanaka Y
Dept. of Neurosurgery, Tokyo Metropolitan Komagome Hospital.
Gan No Rinsho. 1988 Dec;34(15):2036-43.
We have experienced 8 cases of radiation necrosis which occurred following radiation therapy of malignant brain tumors. In all 8 cases, necrosis developed in the brain tissue adjacent to the tumor after intraoperative radiation or interstitial radiation therapy. Considering that the extent of necrosis usually coincides with the extent of the radiation therapy, this type of necrosis is thought to be the expected result of radiation therapy. A differential diagnosis between radiation necrosis and the recurrence of a brain tumor has been thought to be difficult to achieve. Yet with the use of a dynamic CT or an Xe-enhanced CT, differential diagnosis between these two lesions was clearly accomplished.
我们已经遇到了8例恶性脑肿瘤放射治疗后发生的放射性坏死病例。在所有8例病例中，坏死均发生在术中放疗或间质放疗后肿瘤附近的脑组织中。考虑到坏死范围通常与放疗范围一致，这种类型的坏死被认为是放疗的预期结果。人们一直认为，放射性坏死与脑肿瘤复发之间的鉴别诊断很难实现。然而，通过使用动态CT或氙增强CT，这两种病变之间的鉴别诊断得以明确完成。
