Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Laboratório de Bioinformática, LABINFO, Laboratório Nacional de Computação Científica (LNCC), Petrópolis, Rio de Janeiro, Brazil.
Curr Opin Genet Dev. 2020 Jun;62:72-77. doi: 10.1016/j.gde.2020.06.007. Epub 2020 Jul 10.
Focusing on literature published in 2018-2020, we review inferences about: (i) how ancient DNA is contributing to clarify the peopling of the Americas and the dispersal of its first inhabitants, (ii) how the interplay between environmental diversity and culture has influenced the genetic structure and adaptation of Andean and Amazon populations, (iii) how genetics has contributed to our understanding of the Pre-Columbian Tupi expansion in Eastern South America, (iv) the subcontinental origins and dynamics of Post-Columbian admixture in the Americas, and finally, (v) episodes of adaptive natural selection in the American continent, particularly in the high altitudes of the Andes.
聚焦于 2018-2020 年发表的文献，我们综述了以下内容的推断：（i）古 DNA 如何有助于阐明美洲的移民和其最初居民的扩散，（ii）环境多样性与文化之间的相互作用如何影响安第斯山脉和亚马逊地区人群的遗传结构和适应性，（iii）遗传学如何帮助我们理解前哥伦布时期的图皮人在南美洲东部的扩张，（iv）美洲后哥伦布时期混合的次大陆起源和动态，以及（v）适应自然选择的事件，特别是在安第斯山脉的高海拔地区。
