Saravanan Arjunan, Shyamsivappan Selvaraj, Kalagatur Naveen Kumar, Suresh Thangaraj, Maroli Nikhil, Bhuvanesh Nanjan, Kolandaivel Ponmalai, Mohan Palathurai Subramaniam
DRDO-BU CLS, Bharathiar University campus, Coimbatore 641 046, Tamil Nadu, India; School of Chemical Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
School of Chemical Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Nov 5;241:118684. doi: 10.1016/j.saa.2020.118684. Epub 2020 Jul 6.
A new chemosensor (NANH) based on naphthyl moiety was synthesized with good selectivity and sensitivity towards Al ions via the inhibition by operating through dual mechanisms like photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT). The synthesized NANH was validated by various techniques such as H, C NMR and mass spectrum. While prominent fluorescent enhancement was observed from the NANH upon binding with Al ions, however, other metal ions have not responded in the emission spectrum. Detection limit and association constant of NANH for Al were calculated as 1.2 × 10 M and 4.09 × 10 M by using fluorescence titration method. Binding ratio (1:1) of NANH with Al ions were proved by Job's plot and DFT studies. Furthermore, aluminium in variety of water samples was determined, and NANH could be used for biosensing of Al in living cells.
合成了一种基于萘基部分的新型化学传感器（NANH），通过光诱导电子转移（PET）和激发态分子内质子转移（ESIPT）等双重机制抑制作用，对铝离子具有良好的选择性和灵敏度。通过诸如氢谱、碳谱核磁共振以及质谱等各种技术对合成的NANH进行了验证。虽然NANH与铝离子结合时观察到显著的荧光增强，但其他金属离子在发射光谱中没有响应。采用荧光滴定法计算出NANH对铝的检测限和缔合常数分别为1.2×10⁻⁸ M和4.09×10⁵ M。通过Job曲线和密度泛函理论（DFT）研究证明了NANH与铝离子的结合比为1:1。此外，还测定了各种水样中的铝，并且NANH可用于活细胞中铝的生物传感。
