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自体淋巴细胞疗法:既往经验与未来展望。

Autolymphocyte therapy: previous experience and future prospects.

作者信息

Osband M E, Krane R J

机构信息

Joint Clinical Immunotherapy Program, Boston University School of Medicine, Mass.

出版信息

Pathol Immunopathol Res. 1988;7(6):483-93. doi: 10.1159/000157077.

Abstract

Autolymphocyte therapy is outpatient medical treatment for selected patients, in which a relatively small amount of white blood cells is removed temporarily from the patients, modified in the laboratory through sophisticated biotechnology, and returned to the patient for the purpose of enhancing the immune system and contributing to improved health. We suggest that autolymphocyte therapy might be a useful approach in the prevention or treatment of several diseases. Previous work with autolymphocyte therapy in the treatment of metastatic renal cell carcinoma has demonstrated that this approach is minimally toxic and biologically active. Further clinical trials are justified and currently taking place.

摘要

自体淋巴细胞疗法是针对特定患者的门诊治疗方法,即从患者体内暂时取出相对少量的白细胞,在实验室通过先进的生物技术进行处理,然后再回输到患者体内,以增强免疫系统并促进健康改善。我们认为自体淋巴细胞疗法可能是预防或治疗多种疾病的一种有效方法。先前使用自体淋巴细胞疗法治疗转移性肾细胞癌的研究表明,这种方法毒性极小且具有生物活性。进一步的临床试验是合理的,并且正在进行中。

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