Klette H
Inneren Abteilung, St.-Elisabeth-Krankenhauses Halle.
Z Gesamte Inn Med. 1988 Sep 1;43(17):488-91.
It is reported on a 43-year-old patient in whom a mesangio-proliferative glomerulonephritis with nephrotic syndrome was diagnosed 7 months before manifestation of an immunocytoma. Under the treatment of the tumourous disease with chemotherapy and radiation a complete remission of the glomerulonephritis developed. The patient died of a generalized herpes zoster after 2 years 10 months. At the postmortem examination no pathological changes on the kidneys could be proved. After a survey of cases with tumour-associated glomerulonephirits published up to now possible pathogenetic mechanisms and clinical data of the glomerulonephritis as paraneoplastic syndrome are discussed.
据报道,一名43岁患者在免疫细胞瘤出现前7个月被诊断为系膜增生性肾小球肾炎伴肾病综合征。在对肿瘤疾病进行化疗和放疗治疗后,肾小球肾炎完全缓解。患者在2年10个月后死于泛发性带状疱疹。尸检未发现肾脏有病理变化。在对目前已发表的肿瘤相关性肾小球肾炎病例进行综述后,讨论了作为副肿瘤综合征的肾小球肾炎可能的发病机制和临床资料。