Wu Xiao-Li, Liu Li-Xu, Yang Ling-Yu, Zhang Tong
Department of Neurorehabilitation, Rehabilitation Medicine of Capital Medical University, China Rehabilitation Research Centre, Beijing, China.
Medicine (Baltimore). 2020 Jul 10;99(28):e21218. doi: 10.1097/MD.0000000000021218.
Corpus callosum syndrome is a rare consequence of traumatic brain injuries. We provide a case of a patient with typical corpus callosum syndrome following a traumatic brain injury, and demonstrate neural reorganization and significant neural regeneration after comprehensive rehabilitation, using diffusion tensor imaging fiber bundle tracking.
We found typical clinical manifestations of damage to the corpus callosum.
DIAGNOSES, INTERVENTIONS, AND OUTCOMES: We diagnosed a Traumatic Brain Injury (diffuse axonal injury and rupture of corpus callosum). The patient underwent a comprehensive multifaceted rehabilitation program including drug therapy, integrated physical therapy, occupational therapy, acupuncture, music therapy, computer-aided cognitive rehabilitation training, transcranial magnetic stimulation, and hyperbaric oxygen therapy. This rehabilitation program resulted in greatly improved physical and communication ability.
Comprehensive rehabilitation can significantly improve the function of patients with corpus callosum syndrome and may cause neural remodeling, as seen on diffusion tensor imaging.
胼胝体综合征是创伤性脑损伤的罕见后果。我们报告一例创伤性脑损伤后出现典型胼胝体综合征的患者，并通过弥散张量成像纤维束追踪技术，展示了综合康复治疗后神经重组和显著的神经再生情况。
我们发现了胼胝体损伤的典型临床表现。
诊断、干预措施及结果：我们诊断为创伤性脑损伤（弥漫性轴索损伤和胼胝体破裂）。患者接受了包括药物治疗、综合物理治疗、职业治疗、针灸、音乐治疗、计算机辅助认知康复训练、经颅磁刺激和高压氧治疗在内的全面多方面康复计划。该康复计划使患者的身体和沟通能力得到了极大改善。
综合康复可显著改善胼胝体综合征患者的功能，并可能如弥散张量成像所示引起神经重塑。
