Allepot K, Curings P, Viard R, Vincent P-L, Voulliaume D
Centre hospitalier Saint-Joseph Saint-Luc, Lyon, France.
Centre hospitalier Saint-Joseph Saint-Luc, Lyon, France.
Ann Chir Plast Esthet. 2021 Apr;66(2):151-158. doi: 10.1016/j.anplas.2020.06.001. Epub 2020 Jul 11.
Marjolin's ulcer (MU) is a large entity representing skin cancers resulting from the transformation of chronic wounds of a heterogeneous nature. Burn scars are the most at risk of degeneration, in particular because there are the sites of important skin tension. Atypical forms are not uncommon. The objective of this study is to present these exceptions which are underestimated.
All patients with UM in our centre between January 2011 and February 2019 have been included permitting to report the initial pathology, the location, the latency time, the histology and the management carried out.
Eight patients were treated in our center for MU, they developed 16 skin cancers. Fourteen were squamous cell carcinomas (SCC). The shortest latency period was 2 months. The youngest patient was 22 years old when she was diagnosed with MU. Three patients had at least 2 synchronous SCC. One patient had a recurrence after a split-thickness skin grafting on artificial dermis and 2 patients had second locations.
Atypic forms are not rare. MU is commonly recurrent, multiple, early arising and may appear in young people. The treatment of chronic wounds cannot be dissociated from the treatment of contractures, otherwise the wound will inevitably reappear.
马乔林溃疡（MU）是一个大的概念，代表由多种异质性慢性伤口转变而来的皮肤癌。烧伤瘢痕发生退变的风险最高，尤其是因为它们是重要皮肤张力的部位。非典型形式并不罕见。本研究的目的是呈现这些被低估的例外情况。
纳入了2011年1月至2019年2月期间在我们中心患有MU的所有患者，以便报告初始病理、位置、潜伏时间、组织学和所进行的治疗。
我们中心有8例患者因MU接受治疗，他们共发生了16例皮肤癌。其中14例为鳞状细胞癌（SCC）。最短潜伏时间为2个月。最年轻的患者在被诊断为MU时年仅22岁。3例患者至少有2个同步发生的SCC。1例患者在人工真皮上进行分层皮片移植后复发，2例患者有第二个发病部位。
非典型形式并不罕见。MU通常会复发、多发、早期出现且可能出现在年轻人中。慢性伤口的治疗不能与挛缩的治疗分开，否则伤口将不可避免地再次出现。
