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单吻合口十二指肠空肠旁路术作为袖状胃切除术后的翻修或第二步手术。

Single-anastomosis duodenoileal bypass as a revisional or second-step operation after sleeve gastrectomy.

机构信息

Department of Surgery, Hospital Clínico San Carlos, Madrid, Spain.

Department of Endocrinology, Hospital Clínico San Carlos, Madrid, Spain.

出版信息

Surg Obes Relat Dis. 2020 Oct;16(10):1491-1496. doi: 10.1016/j.soard.2020.05.022. Epub 2020 Jun 1.

Abstract

BACKGROUND

One-loop duodenal switch leads to weight loss and improvement or resolution of co-morbidities similar to standard duodenal switch, and it is technically less demanding.

OBJECTIVES

To analyze the weight loss and metabolic improvement after conversion of sleeve gastrectomy to single-anastomosis duodenoileal bypass.

SETTING

University Hospital, Madrid, Spain.

METHODS

This was a retrospective cohort study. Patients submitted to sleeve gastrectomy with insufficient weight loss or programmed for a 2-step surgical approach were included. Single-anastomosis duodenoileostomy was completed if there was no stricture in the stomach and no severe symptoms of gastroesophageal reflux.

RESULTS

Fifty-one patients with a mean initial body mass index of 52 kg/m2 were included. Maximum excess weight loss after the sleeve procedure was 63%. Mean time to the second operation was 36 months. The common channel was 250 cm in 41 patients and 300 cm in 10 patients. The follow-up rate was 77% at 5 years. Excess weight loss and total weight loss were 79% and 39%, respectively, at 1 year from the second surgery and 79% and 41%, respectively, at 5 years. Furthermore, 47% of the patients with diabetes achieved complete remission after sleeve gastrectomy, and 94% achieved remission after conversion to single-anastomosis duodenoileal bypass. Final weight loss was significantly higher in those patients who achieved better weight loss after the sleeve gastrectomy than those who did not.

CONCLUSIONS

Single-anastomosis duodenoileal bypass is a beneficial procedure after sleeve gastrectomy for those who fail to lose weight or those with co-morbidities or as a planned second step.

摘要

背景

单吻合口十二指肠转流术与标准十二指肠转流术一样,可导致体重减轻和改善或解决合并症,且技术要求较低。

目的

分析胃旁路术后转换为单吻合口十二指肠空肠旁路术的体重减轻和代谢改善情况。

设置

西班牙马德里大学医院。

方法

这是一项回顾性队列研究。纳入接受胃旁路术但体重减轻不足或计划采用两步手术的患者。如果胃无狭窄且无严重胃食管反流症状,则完成单吻合口十二指肠空肠吻合术。

结果

共纳入 51 例初始体重指数为 52kg/m2 的患者。袖状胃切除术术后最大超重减轻率为 63%。第二次手术的平均时间为 36 个月。41 例患者共同通道为 250cm,10 例患者共同通道为 300cm。5 年时的随访率为 77%。第二次手术后 1 年,超重减轻和总体重减轻分别为 79%和 39%,5 年时分别为 79%和 41%。此外,47%的糖尿病患者在胃旁路术后完全缓解,94%的患者在转换为单吻合口十二指肠空肠旁路术后缓解。与未达到减重效果的患者相比,那些在袖状胃切除术减重效果较好的患者最终减重效果更显著。

结论

对于那些体重减轻不足或存在合并症的患者,或作为计划的第二步,单吻合口十二指肠空肠旁路术是胃旁路术失败后的有益治疗选择。

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