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头颈部癌症游离皮瓣手术后即刻术后营养不足的原因。

Causes of nutrition deficit during immediate postoperative period after free flap surgery for cancer of the head and neck.

机构信息

Department of Anesthesiology, Medical Research Centre and Research Group of Surgery, Anesthesia and Intensive Care, University of Oulu, Oulu University Hospital, P.O. Box 21, 90029, Oulu, Finland.

出版信息

Eur Arch Otorhinolaryngol. 2021 Apr;278(4):1171-1178. doi: 10.1007/s00405-020-06206-1. Epub 2020 Jul 14.

DOI:10.1007/s00405-020-06206-1
PMID:32666293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7954733/
Abstract

PURPOSE

The aim of the present of study was to examine nutrition deficit during the immediate postoperative in-hospital period following free flap surgery for cancer of the head and neck (HNC). Underfeeding and malnutrition are known to be associated with impaired short- and long-time recovery after major surgery.

METHODS

This single-center retrospective cohort study included 218 HNC patients who underwent free flap surgery in Oulu University Hospital, Finland between the years 2008 and 2018. Nutrition delivery methods, the adequacy of nutrition and complication rates were evaluated during the first 10 postoperative days.

RESULTS

A total of 131 (60.1%) patients reached nutritional adequacy of 60% of calculated individual demand during the follow-up period. According to multivariate analysis, nutrition inadequacy was associated with higher ideal body weight (OR 1.11 [1.04-1.20]), whereas adequate nutrition was associated with higher number of days with oral food intake (OR 0.79 [0.67-0.93]).

CONCLUSION

Inadequate nutrition is common after HNC free flap surgery. The present results suggest that more adequate nutrition delivery might be obtained by the early initiation of oral food intake and close monitoring of nutrition support.

摘要

目的

本研究旨在探讨头颈部癌症(HNC)患者游离皮瓣手术后住院期间即刻术后阶段的营养不足情况。众所周知,术后营养不足和营养不良与大手术后短期和长期恢复受损有关。

方法

本单中心回顾性队列研究纳入了 2008 年至 2018 年期间在芬兰奥卢大学医院接受游离皮瓣手术的 218 例 HNC 患者。评估了术后第 10 天内的营养供给方式、营养充足程度和并发症发生率。

结果

在随访期间,共有 131 例(60.1%)患者达到了 60%的个体需求计算值的营养充足度。多变量分析表明,营养不足与较高的理想体重相关(OR 1.11 [1.04-1.20]),而充足的营养与较高的经口进食天数相关(OR 0.79 [0.67-0.93])。

结论

HNC 游离皮瓣手术后营养不足较为常见。本研究结果表明,通过早期开始经口进食和密切监测营养支持,可能获得更充足的营养供给。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802c/7954733/280539fb4058/405_2020_6206_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802c/7954733/280539fb4058/405_2020_6206_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/802c/7954733/280539fb4058/405_2020_6206_Fig1_HTML.jpg

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