Department of Physical Therapy, University of Alabama at Birmingham , Birmingham, AL, USA.
Expert Rev Neurother. 2020 Aug;20(8):855-865. doi: 10.1080/14737175.2020.1796640. Epub 2020 Aug 1.
The science supporting the application of exercise training and physical activity in persons with multiple sclerosis (MS) has expanded considerably in strength and scope over the past 25+ years. Exercise training is now a strategy that is commonly recommended for management of MS in clinical practice. Yet, there are still many opportunities for expanding the breadth and strength of research on exercise training in MS.
This paper provides the authors' perspective on eight emerging areas of research involving exercise and physical activity behavior in persons living with MS. Those areas include behavior change interventions, research across the activity continuum, telerehabilitation, neuroplasticity, heterogeneity of outcomes, inclusion of targeted samples, combined interventions involving exercise training, and multi-site trials.
Additional research addressing those areas will greatly expand the opportunity for translation of exercise and physical activity into the clinical care of persons with MS.
过去 25 多年来，支持将运动训练和身体活动应用于多发性硬化症（MS）患者的科学依据在强度和范围上都有了显著的扩展。运动训练现在是一种在临床实践中常用于 MS 管理的策略。然而，在 MS 中的运动训练研究仍有许多机会可以扩展其广度和强度。
本文提供了作者对涉及患有 MS 的人群的运动和身体活动行为的八个新兴研究领域的观点。这些领域包括行为改变干预、跨越活动连续体的研究、远程康复、神经可塑性、结果的异质性、目标样本的纳入、包括运动训练的联合干预以及多地点试验。
解决这些领域的额外研究将极大地扩展将运动和身体活动转化为 MS 患者临床护理的机会。
