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2019冠状病毒病的神经血管与灌注成像表现:病例报告及文献综述

Neurovascular and perfusion imaging findings in coronavirus disease 2019: Case report and literature review.

作者信息

Soldatelli Matheus Dorigatti, Amaral Lázaro Faria do, Veiga Viviane Cordeiro, Rojas Salomón Soriano Ordinola, Omar Samir, Marussi Victor Hugo Rocha

机构信息

Department of Neuroradiology, Beneficência Portuguesa de São Paulo, Brazil.

Department of Neurointensive Care, Beneficência Portuguesa de São Paulo, Brazil.

出版信息

Neuroradiol J. 2020 Oct;33(5):368-373. doi: 10.1177/1971400920941652. Epub 2020 Jul 15.

Abstract

Central nervous system involvement in severe acute respiratory syndrome caused by coronavirus disease 2019 (COVID-19) has increasingly been recognised in the literature, and possible mechanisms of neuroinvasion, neurotropism and neurovirulence have been described. Neurological signs have been described in 84% of COVID-19 intensive care unit patients, and haemostatic abnormalities in such patients may play an important role, with a broad spectrum of neuroimaging findings. This report describes the magnetic resonance imaging neurovascular findings in an acutely ill patient with COVID-19, including perfusion abnormalities depicted in the arterial spin labelling technique.

摘要

新型冠状病毒肺炎(COVID-19)所致严重急性呼吸综合征累及中枢神经系统的情况在文献中已得到越来越多的认识,并且已经描述了神经侵袭、神经嗜性和神经毒力的可能机制。84%的COVID-19重症监护病房患者出现了神经症状,此类患者的止血异常可能起重要作用,神经影像学表现广泛。本报告描述了1例急性COVID-19患者的磁共振成像神经血管表现,包括动脉自旋标记技术显示的灌注异常。

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本文引用的文献

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Early postmortem brain MRI findings in COVID-19 non-survivors.COVID-19 死亡病例的死后早期脑部 MRI 研究结果。
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Radiology. 2020 Oct;297(1):E223-E227. doi: 10.1148/radiol.2020202040. Epub 2020 May 21.
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COVID-19-associated Leukoencephalopathy.新型冠状病毒肺炎相关白质脑病
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