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颅内压监测在严重创伤性脑损伤患者中的应用。

Use of Intracranial Pressure Monitoring in Patients with Severe Traumatic Brain Injury.

机构信息

Department of Neurosurgery, State University of New York Upstate Medical University, Syracuse, New York, USA.

Department of Neurosurgery, State University of New York Upstate Medical University, Syracuse, New York, USA.

出版信息

World Neurosurg. 2020 Oct;142:e385-e395. doi: 10.1016/j.wneu.2020.07.022. Epub 2020 Jul 12.

Abstract

OBJECTIVE

The Brain Trauma Foundation (BTF) recommends intracranial pressure (ICP) monitoring for all salvageable patients with an abnormal computed tomography (CT) scan and a Glasgow Coma Scale <9. Studies have shown that compliance with this recommendation is low. We sought to obtain contemporary national rates of ICP monitor placement in patients with severe traumatic brain injury (TBI).

METHODS

Patients from the National Trauma Data Bank from 2013 to 2017 who met BTF criteria for ICP monitoring were included. Placement of an intraparenchymal ICP monitor or an external ventricular drain was queried. Binary logistic regression was used to determine factors that influenced the placement of an ICP monitor.

RESULTS

A total of 21,374 patients with severe TBI and an abnormal CT scan were included in the study. An ICP monitor was placed in 6543 patients (30.6%). ICP monitor placement increased modestly from 28.6% in 2013 to 32.8% in 2017. The pooled odds of ICP monitor placement between 2014 and 2017 were not different from 2013 (odds ratio, 1.04; 95% confidence interval, 0.99-1.09), but the adjusted odds of ICP monitor placement in 2017 were significantly greater (odds ratio, 1.18; 95% confidence interval, 1.06-1.30). Treatment at a teaching hospital, subdural hematoma, multiple intracranial abnormalities on CT, and greater Injury Severity Score were associated with ICP monitor placement, whereas older age was negatively associated with ICP monitor placement.

CONCLUSIONS

The rate of ICP monitoring in patients with severe TBI who meet BTF criteria is low and increased only slightly from 2013 to 2017.

摘要

目的

颅脑创伤基金会(BTF)建议对所有符合异常计算机断层扫描(CT)和格拉斯哥昏迷量表(GCS)<9 分的可挽救患者进行颅内压(ICP)监测。研究表明,对这一建议的依从率较低。我们试图获得目前严重创伤性脑损伤(TBI)患者颅内压监测仪的放置率。

方法

从 2013 年至 2017 年国家创伤数据库中纳入符合 BTF 颅内压监测标准的患者。查询是否放置脑实质内 ICP 监测仪或外部脑室引流管。采用二项逻辑回归确定影响 ICP 监测仪放置的因素。

结果

共纳入 21374 例严重 TBI 且 CT 异常的患者。21374 例患者中有 6543 例(30.6%)放置了 ICP 监测仪。从 2013 年的 28.6%到 2017 年,颅内压监测仪的放置略有增加。2014 年至 2017 年期间,与 2013 年相比,颅内压监测仪放置的总体几率没有差异(比值比,1.04;95%置信区间,0.99-1.09),但 2017 年调整后的颅内压监测仪放置几率明显更高(比值比,1.18;95%置信区间,1.06-1.30)。在教学医院接受治疗、硬膜下血肿、CT 上有多个颅内异常和更高的损伤严重程度评分与 ICP 监测仪放置相关,而年龄较大与 ICP 监测仪放置呈负相关。

结论

符合 BTF 标准的严重 TBI 患者中进行 ICP 监测的比例较低,从 2013 年到 2017 年仅略有增加。

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