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慢性血液透析患者动静脉内瘘狭窄经皮腔内血管成形术后手部和脑部氧合作用降低。

Decrease in hand and cerebral oxygenation after percutaneous transluminal angioplasty for arteriovenous fistula stenosis in a patient on chronic hemodialysis.

作者信息

Shindo Mitsutoshi, Ookawara Susumu, Kovarova Lucie, Morino Junki, Minato Saori, Ito Kiyonori, Malik Jan, Morishita Yoshiyuki

机构信息

Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-City, Saitama-ken 330-8503, Japan.

Third Department of Internal Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic.

出版信息

Radiol Case Rep. 2020 Jul 3;15(9):1493-1495. doi: 10.1016/j.radcr.2020.05.072. eCollection 2020 Sep.

DOI:10.1016/j.radcr.2020.05.072
PMID:32670447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7338991/
Abstract

A 79-year-old woman who was on chronic hemodialysis due to diabetic nephropathy and had previously undergo surgery for radiocephalic arteriovenous fistula (AVF) in her right wrist needed percutaneous transluminal angioplasty (PTA) for stenosis at the juxta-anastomotic access site. After successful PTA, the systemic blood pressure decreased from 144/93 mm Hg to 117/67 mm Hg in response to the increase in AVF blood flow. Furthermore, the regional oxygen saturation (rSO) value in her dorsal hand decreased from 67.9% to 64.9% and, simultaneously, the cerebral rSO decreased from 63.6% to 60.1%. Our experience indicates that the PTA procedure may affect the rapid deterioration of systemic oxygenation, including that in the hand and brain, in association with the increase in the AVF blood flow and change in systemic circulation.

摘要

一名79岁女性因糖尿病肾病接受长期血液透析,此前曾因右腕桡动脉动静脉内瘘(AVF)接受手术,现因吻合口附近通路部位狭窄需要进行经皮腔内血管成形术(PTA)。PTA成功后,随着AVF血流量增加,全身血压从144/93 mmHg降至117/67 mmHg。此外,她手背的局部氧饱和度(rSO)值从67.9%降至64.9%,同时,脑部rSO从63.6%降至60.1%。我们的经验表明,PTA手术可能会随着AVF血流量增加和全身循环变化,影响包括手部和脑部在内的全身氧合迅速恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc0c/7338991/216c90f0f250/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc0c/7338991/216c90f0f250/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc0c/7338991/216c90f0f250/gr1.jpg

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J Am Heart Assoc. 2019 Feb 19;8(4):e011183. doi: 10.1161/JAHA.118.011183.
2
Association of cerebral oxygenation with estimated glomerular filtration rate and cognitive function in chronic kidney disease patients without dialysis therapy.慢性肾脏病非透析患者脑氧合与估计肾小球滤过率及认知功能的相关性研究。
PLoS One. 2018 Jun 25;13(6):e0199366. doi: 10.1371/journal.pone.0199366. eCollection 2018.
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Decrease of muscle strength in vascular access hand due to silent ischaemia.
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Low Cerebral Oxygenation Is Associated with Cognitive Impairment in Chronic Hemodialysis Patients.低脑氧合与慢性血液透析患者的认知障碍有关。
Nephron. 2018;139(2):113-119. doi: 10.1159/000487092. Epub 2018 Feb 13.
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Changes in Cerebral Oxygenation Associated with Intradialytic Blood Transfusion in Patients with Severe Anemia Undergoing Hemodialysis.重度贫血患者血液透析期间进行透析内输血相关的脑氧合变化
Nephron Extra. 2017 Apr 28;7(1):42-51. doi: 10.1159/000471812. eCollection 2017 Jan-Apr.
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Tissue ischemia worsens during hemodialysis in end-stage renal disease patients.在终末期肾病患者的血液透析过程中,组织缺血会加重。
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