Härmä M, Alhava E
Department of Surgery, University Central Hospital, Kuopio, Finland.
Ann Chir Gynaecol. 1988;77(5-6):180-3.
The prevalence of lactose malabsorption (LM) was determined by lactose tolerance tests in 18 women with spinal fragility fractures and 28 women with hip fractures and compared with 35 female controls of the same ethnic background. The association of LM with bone density in the spine, bone mineral density in the distal radius and histomorphometric values of iliac crest biopsies was also evaluated. The prevalence of LM did not differ between the fracture groups and the control subjects. Patients with LM did not differ from those with normal lactose tolerance with regard to bone densitometry or histomorphometric findings in iliac crest biopsies. These results suggest that in Finland LM is not a risk factor for osteopenic fractures in the elderly.
通过乳糖耐量试验测定了18名患有脊柱脆性骨折的女性和28名患有髋部骨折的女性乳糖吸收不良(LM)的患病率,并与35名具有相同种族背景的女性对照进行比较。还评估了LM与脊柱骨密度、桡骨远端骨矿物质密度以及髂嵴活检组织形态计量学值之间的关联。骨折组和对照受试者之间LM的患病率没有差异。在骨密度测定或髂嵴活检的组织形态计量学结果方面,乳糖吸收不良患者与乳糖耐量正常的患者没有差异。这些结果表明,在芬兰,乳糖吸收不良不是老年人骨质疏松性骨折的危险因素。