From the, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
and the, Department of Internal Medicine, Section of Geriatrics, Yale School of Medicine, New Haven, CT, USA.
Acad Emerg Med. 2020 Dec;27(12):1270-1278. doi: 10.1111/acem.14088. Epub 2020 Aug 8.
We have previously shown that older adults discharged from the emergency department (ED) experience an increased disability burden within a 6-month time period after ED discharge. The objective of this study was to identify risk factors associated with increased disability burden among older adults discharged from the ED.
This study is part of an ongoing longitudinal study of 754 community-living persons aged ≥70 years. The analytic sample included 813 ED visits without hospitalization from 430 participants who had at least one visit to an ED during a 14-year follow-up period (1998-2012). Information on ED visits and disability burden in 13 functional activities was collected during monthly interviews. Twenty-nine candidate risk factors were evaluated for their independent associations with increased disability burden using a longitudinal multivariable model.
In the multivariable analyses, age ≥85 (adjusted risk ratio [aRR] = 1.14, 95% confidence interval [CI] = 1.05 to 1.24), being unmarried (aRR = 1.15, 95% CI = 1.05 to 1.27), lower-extremity weakness (aRR = 1.20, 95% CI = 1.07 to 1.34), and physical frailty (aRR = 1.25, 95% CI = 1.13 to 1.37) were associated with increased disability burden. As the number of risk factors increased, the predicted mean disability burden (on a scale of 0 to 13) also increased, ranging from a value of 1.80 (95% CI = 1.43 to 2.27) for 0 risk factors to a value of 8.59 (95% CI = 7.93 to 9.29) for four risk factors.
Among older adults discharged from the ED, several risk factors were associated with increased disability burden over the following 6 months, including age ≥85, being unmarried, lower-extremity weakness, and physical frailty. Further research is needed to evaluate whether risk stratification based on nonmodifiable factors or interventions targeting modifiable risk factors improve functional outcomes for older adults discharged from the ED.
我们之前的研究表明,从急诊科(ED)出院的老年人在 ED 出院后 6 个月内会增加残疾负担。本研究的目的是确定与 ED 出院后老年人残疾负担增加相关的危险因素。
这是一项对 754 名年龄≥70 岁的社区居住者进行的正在进行的纵向研究的一部分。分析样本包括 430 名参与者的 813 次 ED 就诊,这些参与者在 14 年的随访期间(1998-2012 年)至少有一次 ED 就诊。在每月的访谈中收集有关 ED 就诊和 13 项功能活动的残疾负担信息。使用纵向多变量模型评估 29 个候选风险因素与残疾负担增加的独立关联。
在多变量分析中,年龄≥85 岁(调整后的风险比[aRR]为 1.14,95%置信区间[CI]为 1.05 至 1.24)、未婚(aRR 为 1.15,95%CI 为 1.05 至 1.27)、下肢无力(aRR 为 1.20,95%CI 为 1.07 至 1.34)和身体虚弱(aRR 为 1.25,95%CI 为 1.13 至 1.37)与残疾负担增加相关。随着危险因素数量的增加,预测的平均残疾负担(0 到 13 分)也随之增加,从 0 个危险因素的 1.80(95%CI 为 1.43 至 2.27)到 4 个危险因素的 8.59(95%CI 为 7.93 至 9.29)。
在从 ED 出院的老年人中,有几个危险因素与接下来的 6 个月内残疾负担增加相关,包括年龄≥85 岁、未婚、下肢无力和身体虚弱。需要进一步研究评估基于不可改变因素的风险分层或针对可改变危险因素的干预措施是否能改善 ED 出院老年人的功能结局。