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糖尿病性 Pilon 骨折:真有我们想的那么严重吗?

Diabetic Pilon Factures: Are They as Bad as We Think?

机构信息

Department of Orthopaedic Surgery, University of Missouri, Columbia, MO; and.

Missouri Orthopaedic Institute, Columbia, MO.

出版信息

J Orthop Trauma. 2021 Mar 1;35(3):149-153. doi: 10.1097/BOT.0000000000001904.

Abstract

OBJECTIVE

To identify how diabetes impacts the risk of complications requiring further surgery (deep surgical site infection, nonunion, amputation, and arthrodesis) after pilon fracture fixation.

DESIGN

Retrospective cohort study.

SETTING

Level 1 academic trauma center.

PATIENTS

Two hundred seventy-nine pilon fractures (276 patients) were identified. A retrospective review was performed to find patients who presented for open reduction and internal fixation of a tibial pilon fracture (OTA/AO 43). Patient demographics, medical comorbidities, OTA/AO fracture type, and surgical outcomes were reviewed.

INTERVENTION

Patients were stratified into cohorts based on the presence or absence of diabetes at the time of surgery.

MAIN OUTCOME MEASUREMENTS

The complications of interest that proved significant during univariate analyses were then entered into a multivariable logistic regression model using a stepwise method to identify the independent predictors for complications.

RESULTS

There were 43 fractures (15.4%) in patients with diabetes mellitus; 17 (39.5%) of whom were insulin-dependent diabetics. Diabetic patients were significantly more likely to have a higher body mass index (34.81 vs. 29.57, P = 0.002) and be older (55.30 ± 16.3 years vs. 41.70 ± 14.05, P < 0.001) at the time of injury. Patients without diabetes were more likely to sustain an OTA/AO 43-C3 fracture (36.0% vs. 11.6%, P = 0.001). Diabetic patients were 5.5 times more likely to require an arthrodesis [95% confidence interval (CI) = 1.894-16.214; P = 0.001] and 2.7 times more likely to develop a deep infection (95% CI = 1.261-5.630; P = 0.008).

CONCLUSIONS

Overall, diabetic patients in this study were 3.64 times more likely (95% CI = 1.854-7.159; P < 0.001) to experience any complication, despite having less complex fractures.

LEVEL OF EVIDENCE

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

确定糖尿病如何影响 Pilon 骨折固定后需要进一步手术(深部手术部位感染、不愈合、截肢和关节融合)的并发症风险。

设计

回顾性队列研究。

地点

1 级学术创伤中心。

患者

确定了 279 例 Pilon 骨折(276 例患者)。进行回顾性研究以寻找接受胫骨 Pilon 骨折切开复位内固定术(OTA/AO 43)的患者。回顾患者的人口统计学、合并症、OTA/AO 骨折类型和手术结果。

干预

根据手术时是否存在糖尿病,将患者分为队列。

主要观察指标

在单变量分析中证明有显著意义的并发症随后被纳入逐步多变量逻辑回归模型,以确定并发症的独立预测因素。

结果

43 例(15.4%)患者患有糖尿病;其中 17 例(39.5%)为胰岛素依赖型糖尿病患者。糖尿病患者的体质量指数(34.81 与 29.57,P = 0.002)和年龄(55.30 ± 16.3 岁与 41.70 ± 14.05 岁,P < 0.001)明显更高。无糖尿病患者更有可能发生 OTA/AO 43-C3 骨折(36.0%与 11.6%,P = 0.001)。糖尿病患者更有可能需要关节融合术(95%置信区间[CI] = 1.894-16.214;P = 0.001)和更有可能发生深部感染(95% CI = 1.261-5.630;P = 0.008)。

结论

总的来说,与骨折复杂程度较低的患者相比,该研究中的糖尿病患者发生任何并发症的可能性高 3.64 倍(95% CI = 1.854-7.159;P < 0.001)。

证据水平

预后 III 级。有关证据水平的完整说明,请参见作者说明。

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