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本文引用的文献

1
Cerebrospinal Fluid Rhinorrhea and Subsequent Bacterial Meningitis due to an Atypical Clival Fracture.非典型斜坡骨折导致脑脊液鼻漏及继发细菌性脑膜炎
Intern Med. 2017;56(14):1911-1914. doi: 10.2169/internalmedicine.56.8186. Epub 2017 Jul 15.
2
Spontaneous sphenoid sinus cerebrospinal fluid leak and meningoencephalocele - are they due to patent Sternberg's canal?自发性蝶窦脑脊液漏和脑膜脑膨出——它们是由于斯滕伯格管未闭所致吗？
Wideochir Inne Tech Maloinwazyjne. 2015 Jul;10(2):347-58. doi: 10.5114/wiitm.2014.47097. Epub 2014 Dec 3.
3
Spontaneous lateral sphenoid cephaloceles: anatomic factors contributing to pathogenesis and proposed classification.自发性蝶骨外侧颅底脑膨出：发病机制的解剖学因素及分类建议。
AJNR Am J Neuroradiol. 2014 Apr;35(4):784-9. doi: 10.3174/ajnr.A3744. Epub 2013 Oct 3.
4
Pharmacokinetics of moxifloxacin in non-inflamed cerebrospinal fluid of humans: implication for a bactericidal effect.莫西沙星在人非炎性脑脊液中的药代动力学：对杀菌作用的影响。
J Antimicrob Chemother. 2008 Jun;61(6):1328-31. doi: 10.1093/jac/dkn110. Epub 2008 Mar 18.
5
Sphenoid encephaloceles: disease management and identification of lesions within the lateral recess of the sphenoid sinus.蝶骨脑膨出：蝶窦外侧隐窝内病变的疾病管理与识别
Laryngoscope. 2002 Oct;112(10):1800-5. doi: 10.1097/00005537-200210000-00018.

自发性蝶骨脑膜脑膨出伴脓毒症

Spontaneous sphenoid meningoencephalocele with sepsis.

作者信息

Shah Monica, Tadeo Bermúdez Borjas Marco A, Brust Karen

机构信息

Department of Infectious Diseases, Baylor Scott and White Medical Center-TempleTempleTexas.

Escuela de Medicina y Ciencias de la Salud TecSalud, Instituto Tecnológico y de Estudios Superiores de MonterreyMonterreyMexico.

出版信息

Proc (Bayl Univ Med Cent). 2020 May 13;33(3):442-443. doi: 10.1080/08998280.2020.1756631. eCollection 2020 Jul.

DOI:10.1080/08998280.2020.1756631
PMID:32675980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7340480/
Abstract

Streptococci bacteremia is an unusual source of sepsis from spontaneous cerebrospinal fluid (CSF) rhinorrhea due to sphenoid meningoencephalocele. A spontaneous cause of CSF rhinorrhea should be on the differential along with trauma and congenital and neoplastic lesions. Moxifloxacin 400 mg daily for 2 weeks has a satisfactory CSF penetration to treat bacteremia due to CSF rhinorrhea.

摘要

链球菌菌血症是蝶骨脑膜脑膨出导致自发性脑脊液鼻漏引起败血症的罕见来源。脑脊液鼻漏的自发原因应与创伤、先天性和肿瘤性病变一起列入鉴别诊断。每日400毫克莫西沙星，连用2周，对治疗脑脊液鼻漏引起的菌血症有令人满意的脑脊液穿透性。