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严重曲霉性角膜炎病例中的大植片穿透性角膜移植术

Large graft tectonic penetrating keratoplasty in a case of severe aspergillus keratitis.

作者信息

Bromeo Albert John, Aquino-Alegre Elenor Reina, Lim Bon Siong Ruben

机构信息

Department of Ophthalmology and Visual Sciences, Sentro Oftalmologico Jose Rizal, Philippine General Hospital, University of the Philippines, Manila, Philippines.

出版信息

GMS Ophthalmol Cases. 2020 Apr 2;10:Doc17. doi: 10.3205/oc000144. eCollection 2020.

Abstract

Penetrating keratoplasty is indicated for cases of severe microbial keratitis, particularly if associated with impending corneal perforation. The case report details a 45-year-old male farmer who consulted for blurring of vision in the left eye after an incident wherein mud was flung onto his eye during farming. He noted eye redness and a growing opacity on his left eye. He was initially treated with topical antimicrobial and corticosteroid medication which did not resolve his symptoms. He presented with a visual acuity of hand movement on the affected eye. Slit lamp examination showed a large protruding mound-like plaque, occupying almost the entire corneal surface of the left eye, with associated scleritis. The ocular ultrasound was unremarkable. The patient was diagnosed with fungal keratitis, which culture from corneal scraping showed to be from an infection with . A tectonic penetrating keratoplasty with 360-degree iridectomy, lens extraction, and anterior vitrectomy was immediately done, and a regimen consisting of topical natamycin was started. Despite the severe presentation of the fungal corneal infection, the eye was fortunately salvaged.

摘要

穿透性角膜移植术适用于严重的微生物性角膜炎病例,特别是伴有即将发生角膜穿孔的情况。该病例报告详细描述了一名45岁的男性农民,他在务农时眼睛被溅入泥浆后出现左眼视力模糊而前来就诊。他注意到左眼发红且混浊不断加重。他最初接受了局部抗菌和皮质类固醇药物治疗,但症状并未缓解。他就诊时患眼视力仅为手动。裂隙灯检查显示左眼角膜表面有一个巨大的突出丘状斑块,几乎占据了整个角膜表面,并伴有巩膜炎。眼部超声检查未见异常。患者被诊断为真菌性角膜炎,角膜刮片培养显示感染了……。立即进行了360度虹膜切除术、晶状体摘除术和前部玻璃体切除术的结构性穿透性角膜移植术,并开始使用局部那他霉素治疗方案。尽管真菌性角膜感染表现严重,但幸运的是患眼得以挽救。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/220b/7332714/d39e77f13263/OC-10-17-g-001.jpg

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