Rath Soveeta, Ganesh Suma, Mathur Umang, Sharma Manasvini
Department of Pediatric Ophthalmology and Strabismus, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
Department of Cornea and Anterior Segment Services, Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.
GMS Ophthalmol Cases. 2020 Apr 3;10:Doc20. doi: 10.3205/oc000147. eCollection 2020.
To describe a case of surgically induced scleral necrosis in Treacher Collins syndrome after strabismus surgery. A 19-year-old girl underwent bilateral squint surgery. Two weeks postoperatively, she presented with subconjunctival abscess in the left eye. The surrounding conjunctiva was markedly inflamed with raised edges. Surgical debridement, microbiological evaluation and medical management were started immediately. Screening for autoimmune and vasculitic conditions did not provide any positive results. On subsequent follow-up, conjunctival retraction and an area of scleral necrosis with thinning was noted. Significant healing with antibiotics and steroids was noted within one week. The integrity of the globe was well maintained and no further procedure for tectonic support was performed. Surgically induced scleral necrosis can be immune-mediated or following surgical site infection. Pre-existing scleral thinning due to neuroectodermal apoptosis in Treacher Collins syndrome remains a possible explanation for the accelerated necrotising scleritis in our case.
描述1例患有特雷彻·柯林斯综合征的患者在斜视手术后发生手术诱发巩膜坏死的病例。一名19岁女孩接受了双侧斜视手术。术后两周,她左眼出现结膜下脓肿。周围结膜明显发炎,边缘隆起。立即开始进行手术清创、微生物学评估和药物治疗。自身免疫和血管炎相关病症筛查未得到任何阳性结果。在随后的随访中,发现结膜退缩以及一处巩膜坏死且变薄的区域。一周内可见抗生素和类固醇治疗后有明显愈合。眼球完整性得到良好维持,未进行进一步的结构性支撑手术。手术诱发的巩膜坏死可能是免疫介导的,也可能继发于手术部位感染。由于特雷彻·柯林斯综合征中神经外胚层凋亡导致的巩膜预先变薄,仍是我们病例中加速性坏死性巩膜炎的一个可能解释。