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带蒂空肠与结肠管道用于食管重建的效果比较。

Comparison of outcomes of pedicled jejunal and colonic conduit for esophageal reconstruction.

作者信息

Jiang Sicong, Guo Changying, Zou Bin, Xie Jianguo, Xiong Zhihui, Kuang Yukang, Tang Jianjun

机构信息

Department of Thoracic Surgery, Jiangxi Cancer Hospital of Nanchang University, No. 519 Beijing East Road, Nanchang, 330006, Jiangxi, China.

Department of Obstetrics, Tongde Hospital of Zhejiang Provience, Zhejiang, 310012, Hangzhou, China.

出版信息

BMC Surg. 2020 Jul 16;20(1):156. doi: 10.1186/s12893-020-00810-y.

DOI:10.1186/s12893-020-00810-y
PMID:32677925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7364600/
Abstract

BACKGROUND

At present, the gastric tube is the first choice for esophageal reconstruction after esophagectomy for various benign and malignant diseases. However, when the stomach is not available, a pedicled jejunum or colon is used to reconstruct the esophagus. The present study aimed to compare the postoperative outcomes and quality of life of patients receiving jejunal and colonic conduits.

METHODS

In the present retrospective study, the clinical data of 71 patients with esophageal carcinoma, who received jejunal reconstruction (jejunum group, n = 34) and colonic reconstruction (colon group, n = 37) from 2005 to 2015, were compared.

RESULTS

Compared with the colon group, the jejunum group had a lower incidence of postoperative anastomotic leakage, lesser duration of postoperative drainage, and faster recovery. Furthermore, the scores were better in the jejunum group than in the colon group, in terms of short-term overall quality of life, physical function and social relationships. Moreover, the jejunal group had a significantly lower frequency of pH < 4 simultaneous reflux time > 5 min (N45) and the longest reflux time (LT) at 24 weeks after surgery.

CONCLUSION

In esophageal cancer, when gastric tube construction is not feasible, a pedicled jejunum may be preferred over a colonic conduit due to lower incidence of acid reflux, anastomotic leakage and higher postoperative short-term quality of life, and rapid postoperative recovery.

摘要

背景

目前,胃管是各种良恶性疾病食管切除术后食管重建的首选。然而,当无法利用胃时,则采用带蒂空肠或结肠来重建食管。本研究旨在比较接受空肠和结肠管道重建患者的术后结局及生活质量。

方法

在本回顾性研究中,比较了2005年至2015年间71例接受空肠重建(空肠组,n = 34)和结肠重建(结肠组,n = 37)的食管癌患者的临床资料。

结果

与结肠组相比,空肠组术后吻合口漏发生率更低,术后引流时间更短,恢复更快。此外,在短期总体生活质量、身体功能和社会关系方面,空肠组的评分优于结肠组。而且,空肠组术后24周时pH < 4且同时反流时间> 5分钟(N45)的频率显著更低,反流最长时间(LT)也最短。

结论

在食管癌中,当无法进行胃管构建时,由于酸反流、吻合口漏发生率较低,术后短期生活质量较高且术后恢复较快,带蒂空肠可能比结肠管道更受青睐。

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1
Acid Secretion and Its Relationship to Esophageal Reflux Symptom in Patients with Subtotal Gastrectomy.胃大部切除术后患者的胃酸分泌与食管反流症状的关系。
Dig Dis Sci. 2018 Mar;63(3):703-712. doi: 10.1007/s10620-018-4923-9. Epub 2018 Jan 25.
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Influence of esophagectomy on the gastroesophageal reflux in patients with esophageal cancer.食管癌切除术对食管癌患者胃食管反流的影响。
Dis Esophagus. 2017 Dec 1;30(12):1-7. doi: 10.1093/dote/dox106.
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Long-term functional outcomes after replacement of the esophagus with gastric, colonic, or jejunal conduits: a systematic literature review.
食管癌回结肠移植与胃管道重建的比较结果:生存、生活质量和围手术期风险的倾向匹配分析
Ann Surg Oncol. 2025 May 26. doi: 10.1245/s10434-025-17516-1.
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First experience with a supercharged pedicled jejunal interposition for esophageal replacement after caustic ingestion in a middle-income Latin American country.在一个中等收入的拉丁美洲国家,首次使用带蒂空肠增压移植术治疗腐蚀性物质摄入后食管置换的经验。
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Surgical outcomes and quality of life assessment of esophagectomy for cancer with colon conduit via retrosternal route.经胸骨后路径行结肠管代食管术治疗食管癌的手术效果和生活质量评估。
Esophagus. 2023 Jul;20(3):435-444. doi: 10.1007/s10388-023-00984-3. Epub 2023 Jan 6.
采用胃、结肠或空肠导管替代食管后的长期功能结局:一项系统文献综述
Dis Esophagus. 2017 Dec 1;30(12):1-11. doi: 10.1093/dote/dox083.
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Clinical outcome of using gastric remnant or jejunum or colon conduit in surgery for esophageal carcinoma with previous gastrectomy.在既往接受过胃切除术的食管癌手术中使用胃残端或空肠或结肠通道的临床结果。
J Surg Oncol. 2017 May;115(6):729-737. doi: 10.1002/jso.24564. Epub 2017 Feb 14.
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Reconstruction after esophagectomy for esophageal cancer patients with a history of gastrectomy.有胃切除史的食管癌患者行食管切除术后的重建。
Gen Thorac Cardiovasc Surg. 2016 Aug;64(8):457-63. doi: 10.1007/s11748-016-0661-0. Epub 2016 May 27.
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Cancer statistics in China, 2015.《中国癌症统计数据 2015》
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Long-term Quality of Life After Distal Subtotal and Total Gastrectomy: Symptom- and Behavior-oriented Consequences.远端胃次全切除术和全胃切除术后的长期生活质量:以症状和行为为导向的后果
Ann Surg. 2016 Apr;263(4):738-44. doi: 10.1097/SLA.0000000000001481.
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Feasibility of esophageal reconstruction using a pedicled jejunum with intrathoracic esophagojejunostomy in the upper mediastinum for esophageal cancer.利用带蒂空肠行胸段食管空肠吻合术在上纵隔重建食管癌食管的可行性。
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Jejunal graft conduits after esophagectomy.食管切除术后的空肠移植管道
J Thorac Dis. 2014 May;6 Suppl 3(Suppl 3):S333-40. doi: 10.3978/j.issn.2072-1439.2014.05.07.
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Long-term outcome and quality of life after supercharged jejunal interposition for oesophageal replacement.食管置换采用带蒂空肠间置术后的长期结局及生活质量
Surgeon. 2015 Aug;13(4):187-93. doi: 10.1016/j.surge.2014.01.004. Epub 2014 Feb 4.