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自我管理干预对心力衰竭的影响:随机对照试验的系统评价和荟萃分析。

Effects of self-management interventions on heart failure: Systematic review and meta-analysis of randomized controlled trials.

机构信息

School of Nursing, Cheeloo College of Medicine, Shandong University, 44# Wenhua Xi Road, Jinan, Shandong 250012, PR China.

School of Nursing, Cheeloo College of Medicine, Shandong University, 44# Wenhua Xi Road, Jinan, Shandong 250012, PR China.

出版信息

Int J Nurs Stud. 2020 Oct;110:103689. doi: 10.1016/j.ijnurstu.2020.103689. Epub 2020 Jun 16.

Abstract

BACKGROUND

Self-management intervention is an important component of disease management in patients with heart failure. It can improve heart failure knowledge, quality of life, and heart failure-related hospitalizations of heart failure patients. However, studies on the effect of two self-management interventions tasks have reported conflicting results.

OBJECTIVE

This study conducted an up-to-date systematic review of the literature to evaluate the effects of self-management interventions on heart failure knowledge, quality of life, and heart failure-related hospitalizations in patients with heart failure.

DESIGN

Systematic review and meta-analysis.

DATA SOURCES

We searched PubMed, Embase, Web of Science, Cochrane Library, and the references of articles in 14th December 2019.

METHODS

The study characteristics included: authors, year, country, sample size, mean age of patients with heart failure, duration of intervention, recruitment and intervention delivery, interventions based on self-efficacy theory, cognitive behavioral therapy, disease management, self-care education. The risk of bias for each study was assessed independently by two investigators based on the Cochrane Handbook. This study used Revman to analyze different research outcomes. The fixed-effect model was used in the absence of significant heterogeneity or low heterogeneity, and if the heterogeneity was high, the random effect model was used.

RESULTS

A total of 4977 publications were retrieved in this study. After eliminating duplicates and screening for titles and abstracts, 209 articles were retrieved for full-text evaluation. Finally, a total sample size analyzed across 15 randomized controlled trials was 2630 participants. This study showed that self-management interventions significantly improved heart failure knowledge (0.61, 95% confidence interval (CI) 0.27-0.95, p = 0.0004), quality of life (0.20, 95% CI 0.02-0.38, p = 0.03), and heart failure-related hospitalization (OR 0.40, 95% CI 0.29 to 0.55, p<0.00001) in patients with heart failure.

CONCLUSIONS

This study reveals the beneficial effects of self-management interventions on heart failure knowledge, quality of life, and heart failure-related hospitalization in patients with heart failure. Therefore, high quality randomized controlled designs are needed to explore the optimal self-management interventions for patients with heart failure. Tweetable abstract: This study reveals self-management interventions can improve heart failure knowledge, quality of life, and reduced heart failure-related hospitalization.

摘要

背景

自我管理干预是心力衰竭患者疾病管理的重要组成部分。它可以提高心力衰竭患者的心力衰竭知识、生活质量和心力衰竭相关住院率。然而,关于两种自我管理干预任务效果的研究结果却相互矛盾。

目的

本研究对文献进行了最新的系统评价,以评估自我管理干预对心力衰竭患者心力衰竭知识、生活质量和心力衰竭相关住院率的影响。

设计

系统评价和荟萃分析。

资料来源

我们于 2019 年 12 月 14 日检索了 PubMed、Embase、Web of Science、Cochrane Library 和文章参考文献。

方法

研究特征包括:作者、年份、国家、样本量、心力衰竭患者的平均年龄、干预持续时间、招募和干预措施的实施、基于自我效能理论、认知行为疗法、疾病管理、自我护理教育的干预措施。两位研究者独立根据 Cochrane 手册评估每项研究的偏倚风险。本研究使用 Revman 分析不同的研究结果。如果没有显著的异质性或低异质性,则使用固定效应模型,如果异质性高,则使用随机效应模型。

结果

本研究共检索到 4977 篇文献。经过重复项消除和标题与摘要筛选,共检索到 209 篇文章进行全文评估。最终,共有 15 项随机对照试验的 2630 名参与者进行了总样本量分析。本研究表明,自我管理干预显著提高了心力衰竭患者的心力衰竭知识(0.61,95%置信区间(CI)0.27-0.95,p=0.0004)、生活质量(0.20,95%CI 0.02-0.38,p=0.03)和心力衰竭相关住院率(OR 0.40,95%CI 0.29-0.55,p<0.00001)。

结论

本研究揭示了自我管理干预对心力衰竭患者心力衰竭知识、生活质量和心力衰竭相关住院率的有益影响。因此,需要高质量的随机对照设计来探索心力衰竭患者最佳的自我管理干预措施。

可分享摘要

本研究揭示了自我管理干预可以改善心力衰竭患者的心力衰竭知识、生活质量和减少心力衰竭相关住院率。

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