Department of Sport and Computing, Pablo de Olavide University, 41013 Sevilla, Spain.
Instituto de Investigación Hospital 12 de Octubre (i+12), 28041 Madrid, Spain.
Int J Environ Res Public Health. 2020 Jul 15;17(14):5091. doi: 10.3390/ijerph17145091.
A supervised combined training program was applied to a sedentary 56-year-old man with idiopathic pulmonary fibrosis (IPF) along three years, until lung transplantation. It included: (a) aerobic continuous (CT) and interval training (IT), (b) high load resistance training (RT) and (c) inspiratory muscle training (IMT). IT and IMT were applied for two years, while CT and RT could be maintained until transplantation using supplemental oxygen. Maximal inspiratory pressure (MIP) kept above 180 cm HO and forced vital capacity (FVC) remained stable until lung transplantation. Peak oxygen uptake VO increased during 1.5 years before its decline, staying above the poor prognosis level two years. Finally, the patient maintained his walking capacity and independence for 2 years, before the decline due to the disease. After receiving a two-lung transplant, the patient remained intubated for 12 h, left the intensive care unit after 3.5 days and was discharged after 18 days (average values: 48 h, 7-10 days and 25-35 days, respectively). These results show that systematic and supervised combined training can be safety applied in an IPF patient to maintain functionality and quality of life. In addition, we show that RT can be maintained for as long as necessary without complications.
对一位患有特发性肺纤维化（IPF）的 56 岁久坐男性患者进行了为期三年的监督综合训练，直到进行肺移植。该训练包括：（a）有氧运动持续训练（CT）和间歇训练（IT），（b）高负荷阻力训练（RT）和（c）吸气肌训练（IMT）。IT 和 IMT 应用了两年，而 CT 和 RT 可以在使用补充氧气的情况下维持到移植。最大吸气压力（MIP）保持在 180cmHO 以上，用力肺活量（FVC）在肺移植前保持稳定。峰值摄氧量 VO 在下降前的 1.5 年内增加，保持在预后不良的水平两年。最后，患者在疾病导致下降之前，维持了两年的步行能力和独立性。接受双肺移植后，患者仍被插管 12 小时，3.5 天后离开重症监护病房，18 天后出院（平均值：48 小时、7-10 天和 25-35 天）。这些结果表明，系统的和监督的综合训练可以安全地应用于 IPF 患者，以维持其功能和生活质量。此外，我们还表明，RT 可以在没有并发症的情况下维持尽可能长的时间。
