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由水凝胶纳米颗粒热诱导形成玻璃态

Thermally-induced glass formation from hydrogel nanoparticles.

作者信息

Missirlis D, Hubbell J A, Tirelli N

机构信息

Department of Materials and Institute of Biomedical Engineering, ETH Zurich and the University of Zurich, Moussonstrasse 18, CH-8044, Zurich, Switzerland.

School of Pharmacy and Molecular Materials Center, University of Manchester, Oxford Road, Manchester, United KingdomM13 9PL.

出版信息

Soft Matter. 2006 Nov 15;2(12):1067-1075. doi: 10.1039/b607437e.

Abstract

Amphiphilic hydrogel nanoparticles, composed of covalently cross-linked Pluronic F127 and PEG, exhibit a temperature- and concentration-dependent gelation in water which is interpreted as a colloidal glass formation. The possible applications of these phenomena in biomaterials and controlled release are also discussed.

摘要

由共价交联的普朗尼克F127和聚乙二醇组成的两亲性水凝胶纳米颗粒在水中表现出温度和浓度依赖性凝胶化,这被解释为胶体玻璃的形成。还讨论了这些现象在生物材料和控释中的可能应用。

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