A paradigm shift in the field of molecular recognition at the air-water interface: from static to dynamic.

The air-water interface has been recognized as a useful medium for implementation of molecular recognition of aqueous guests since the initial reports of that phenomenon in 1985. Generally, however, there has been no emphasis on the dynamism of the air-water interface despite the fact that that is one of its most unique characteristics, especially when compared with other solid surfaces. In this review, we introduce several of the advances in molecular recognition from the viewpoint of their dynamic properties. Finally, molecular recognition through dynamic cavity formation at the air-water interface is highlighted as being the most advanced example. In the field of molecular recognition, it is clear that a paradigm shift from static to dynamic has been realized.