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评估肛门直肠畸形修补术后粪便失禁患者再次手术的获益。

Assessing the benefit of reoperations in patients who suffer from fecal incontinence after repair of their anorectal malformation.

机构信息

Department of Pediatric Colorectal and Pelvic Reconstructive Surgery, Nationwide Children's Hospital, Columbus, OH.

Department of Pediatric Colorectal and Pelvic Reconstructive Surgery, Nationwide Children's Hospital, Columbus, OH.

出版信息

J Pediatr Surg. 2020 Oct;55(10):2159-2165. doi: 10.1016/j.jpedsurg.2020.06.011. Epub 2020 Jun 17.

DOI:10.1016/j.jpedsurg.2020.06.011
PMID:32682544
Abstract

BACKGROUND AND AIM

Patients with a previously repaired anorectal malformation (ARM) can suffer from complications which lead to incontinence. Reoperation can improve the anatomic result, but its impact on functional outcomes is unclear.

METHODS

We performed a retrospective cohort study of patients with a previously repaired ARM who underwent redo PSARP at our Center and compared results at initial assessment and 12 months after redo.

RESULTS

One hundred fifty-three patients underwent a redo PSARP for anoplasty mislocation (n=93, 61%), stricture (n=55, 36%), remnant of the original fistula (n=28, 18%), or rectal prolapse (n=11, 7%). Post-redo complications included stricture (n=33, 22%) and dehiscence (n=5, 3%). At 1-year post-redo, 75/153 (49%) are on laxatives only, of whom 57 (76%) are continent of stool. Of the remaining 78 (51%) patients, 61 (78%) are clean (≤1 accident per week) on enemas. Interestingly, 16/79 (20%) of patients with expected poor continence potential were continent of stool on laxatives. Overall, 118/153 (77%) are clean after their redo. Quality of life (76.7 vs. 83.8, p=0.05) and Baylor continence (29.2 vs. 17.7, p=<0.0001) scores improved.

CONCLUSION

Patients with fecal incontinence after an ARM repair can, with a reoperation, have their anatomy corrected which can restore continence for many, and improve their quality of life.

LEVEL OF EVIDENCE

IV.

TYPE OF STUDY

Retrospective cohort study.

摘要

背景与目的

先前接受过肛门直肠畸形(ARM)修复的患者可能会出现导致失禁的并发症。再次手术可以改善解剖结果,但对功能结果的影响尚不清楚。

方法

我们对在我们中心接受再次经肛门直肠成形术(PSARP)的先前修复过的 ARM 患者进行了回顾性队列研究,并比较了初次评估和再次手术后 12 个月的结果。

结果

153 例患者因肛门位置错位(93 例,61%)、狭窄(55 例,36%)、原瘘管残留(28 例,18%)或直肠脱垂(11 例,7%)接受再次 PSARP。再次手术后的并发症包括狭窄(33 例,22%)和裂开(5 例,3%)。再次手术后 1 年,75/153(49%)例仅使用轻泻药,其中 57(76%)例大便失禁。其余 78(51%)例患者中,61(78%)例使用灌肠剂时保持清洁(每周≤1 次意外)。有趣的是,16/79(20%)预期有较差控便能力的患者使用轻泻药时大便失禁。总体而言,118/153(77%)例患者再次手术后保持清洁。生活质量(76.7 分比 83.8 分,p=0.05)和 Baylor 控便评分(29.2 分比 17.7 分,p<0.0001)有所改善。

结论

先前接受过 ARM 修复的大便失禁患者可以通过再次手术纠正解剖结构,使许多患者恢复控便能力,并改善生活质量。

证据水平

IV 级

研究类型

回顾性队列研究

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