Millingen K S, Yeo P T, Kamaldeen S
Department of Medicine, University of Tasmania.
Clin Exp Neurol. 1987;24:153-8.
In view of the conflicting evidence concerning prolongation of the VERs in diabetes, pattern reversal VERs were performed on 60 diabetic inpatients. Only in one patient was the VER unequivocally delayed without some other explanation and in 2 other patients it was prolonged in association with proliferative retinopathy. In the latter instance the latency may have been increased by involvement of the maculo-papillary fibres of the optic nerve which may occur during their passage through the retina. Otherwise the study does not strongly support the concept of optic neuropathy or central encephalopathy of the visual system in diabetes, at least as far as can be demonstrated by visual evoked cortical responses to pattern reversal stimuli.
鉴于有关糖尿病患者视觉诱发电位(VERs)延长的证据相互矛盾,我们对60例糖尿病住院患者进行了图形翻转视觉诱发电位检查。只有1例患者的VER明确延迟且无其他解释,另外2例患者的VER延长与增殖性视网膜病变有关。在后一种情况下,潜伏期可能因视神经黄斑乳头纤维在穿过视网膜时受累而增加。否则,该研究并不强烈支持糖尿病患者存在视神经病变或视觉系统中枢脑病的概念,至少就图形翻转刺激的视觉诱发电位皮层反应所能证明的而言。