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瓣周漏封堵装置的晚期移位

Late Migration of a Paravalvular Leak Closure Device.

作者信息

Bottino Roberta, Tirado-Conte Gabriela, McInerney Angela, Noriega Francisco, Nuñez-Gil Ivan, Salinas Pablo, Ferrera Carlos, Jimenez-Quevedo Pilar, Viana-Tejedor Ana, Nombela-Franco Luis

机构信息

Instituto Cardiovascular, Hospital Clínico San Carlos, IdISSC. Universidad Complutense.

出版信息

Int Heart J. 2020 Jul 30;61(4):843-847. doi: 10.1536/ihj.19-512. Epub 2020 Jul 18.

DOI:10.1536/ihj.19-512
PMID:32684589
Abstract

Paravalvular leak (PVL) is a serious complication of surgical valve replacement, often affecting elderly, multimorbid, high-risk patients. The risk of surgical intervention is often prohibitive in these cases, and so percutaneous PVL closure emerged as a feasible and effective management strategy, with a low complication rate. Specific devices for closure of PVL's are currently not widely available, and so PVLs are closed using generic vascular closure devices, which may result in residual paravalvular regurgitation or even closure device displacement. Although rare, late displacement of the closure device with prosthetic impingement can be life threatening, requiring urgent intervention.We present a case of a seventy-year-old gentleman with rheumatic heart disease and multiple previous mechanical aortic and mitral valve replacements. After repeated admissions for decompensated heart failure, secondary to paravalvular mitral regurgitation, a percutaneous paravalvular leak closure was performed with successful reduction of the leak. He represented 30 days later with cardiogenic shock and multiorgan failure secondary to torrential central mitral regurgitation caused by late displacement of the closure device with mitral prosthesis impingement. Due to an excessively high surgical risk, his case was successfully managed percutaneously with retrieval of the displaced device and closure of the PVL using two Amplatzer Vascular Plug III devices. At the six-month review, he remains asymptomatic.Percutaneous PVL closure is an effective strategy for patients with prohibitive surgical risk. Late closure device displacement can be a life-threatening complication. Our case demonstrates that percutaneous management of this complication is feasible even in patients presenting in extremis.

摘要

瓣周漏(PVL)是外科瓣膜置换术的一种严重并发症,常影响老年、多病、高危患者。在这些情况下,手术干预的风险通常过高,因此经皮PVL封堵术成为一种可行且有效的治疗策略,并发症发生率较低。目前用于封堵PVL的特定装置并不广泛可用,因此使用通用血管封堵装置来封堵PVL,这可能导致瓣周残余反流甚至封堵装置移位。尽管罕见,但封堵装置晚期移位并伴有假体撞击可能危及生命,需要紧急干预。我们报告一例70岁男性患者,患有风湿性心脏病,既往多次进行机械主动脉瓣和二尖瓣置换术。因瓣周二尖瓣反流继发失代偿性心力衰竭反复入院后,进行了经皮瓣周漏封堵术,漏口成功减小。30天后,他因封堵装置晚期移位并伴有二尖瓣假体撞击导致严重的中心性二尖瓣反流继发心源性休克和多器官功能衰竭再次就诊。由于手术风险过高,成功对其进行了经皮治疗,取出移位装置并使用两个Amplatzer血管封堵器III型装置封堵PVL。在六个月的复查中,他仍无症状。经皮PVL封堵术是手术风险过高患者的有效策略。封堵装置晚期移位可能是一种危及生命的并发症。我们的病例表明,即使对于处于危急状态就诊的患者,经皮处理这种并发症也是可行的。

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