• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小儿胆汁淤积症:流行病学、遗传学、诊断及当前治疗方法

Pediatric Cholestasis: Epidemiology, Genetics, Diagnosis, and Current Management.

作者信息

Karpen Saul J

机构信息

Department of Pediatrics Division of Pediatric Gastroenterology, Hepatology and Nutrition Emory University School of Medicine/Children's Healthcare of Atlanta Atlanta GA.

出版信息

Clin Liver Dis (Hoboken). 2020 Apr 4;15(3):115-119. doi: 10.1002/cld.895. eCollection 2020 Mar.

DOI:10.1002/cld.895
PMID:32685137
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7346681/
Abstract

Watch a video presentation of this article Watch an interview with the author Answer questions and earn CME.

摘要

观看本文的视频演示 观看对作者的采访 回答问题并获得继续医学教育学分。

相似文献

1
Pediatric Cholestasis: Epidemiology, Genetics, Diagnosis, and Current Management.小儿胆汁淤积症:流行病学、遗传学、诊断及当前治疗方法
Clin Liver Dis (Hoboken). 2020 Apr 4;15(3):115-119. doi: 10.1002/cld.895. eCollection 2020 Mar.
2
Molecular Mechanisms Linking Nonalcoholic Steatohepatitis to Cancer.将非酒精性脂肪性肝炎与癌症联系起来的分子机制
Clin Liver Dis (Hoboken). 2021 Feb 1;17(1):6-10. doi: 10.1002/cld.1006. eCollection 2021 Jan.
3
Nutritional Management of Cholestasis.胆汁淤积的营养管理
Clin Liver Dis (Hoboken). 2020 Feb 25;15(1):9-12. doi: 10.1002/cld.865. eCollection 2020 Jan.
4
Managing the Symptoms and Complications of Cholestasis.胆汁淤积症状及并发症的管理
Clin Liver Dis (Hoboken). 2020 Apr 4;15(3):120-124. doi: 10.1002/cld.901. eCollection 2020 Mar.
5
The Pathophysiology of Cholestasis and Its Relevance to Clinical Practice.胆汁淤积的病理生理学及其与临床实践的相关性。
Clin Liver Dis (Hoboken). 2020 Apr 4;15(3):110-114. doi: 10.1002/cld.894. eCollection 2020 Mar.
6
Novel Therapies for Managing Cholestasis.治疗胆汁淤积的新型疗法
Clin Liver Dis (Hoboken). 2020 Apr 4;15(3):95-99. doi: 10.1002/cld.886. eCollection 2020 Mar.
7
Insights Into Metabolic Mechanisms and Their Application in the Treatment of NASH.非酒精性脂肪性肝炎代谢机制的见解及其在治疗中的应用。
Clin Liver Dis (Hoboken). 2021 Feb 1;17(1):29-32. doi: 10.1002/cld.1062. eCollection 2021 Jan.
8
Nonalcoholic Fatty Liver Disease and Cardiovascular Disease.非酒精性脂肪性肝病与心血管疾病
Clin Liver Dis (Hoboken). 2021 Feb 1;17(1):19-22. doi: 10.1002/cld.1017. eCollection 2021 Jan.
9
Management of Hepatitis C-Infected Patients After Sustained Virological Response.丙型肝炎感染患者持续病毒学应答后的管理
Clin Liver Dis (Hoboken). 2020 Jul 21;16(1):20-24. doi: 10.1002/cld.913. eCollection 2020 Jul.
10
Isolated Elevated Bilirubin.孤立性胆红素升高
Clin Liver Dis (Hoboken). 2020 May 7;15(4):153-156. doi: 10.1002/cld.944. eCollection 2020 Apr.

引用本文的文献

1
Newly Described Mutations of the Gene in Infants with Jaundice and Pruritus.黄疸和瘙痒婴儿中该基因新发现的突变
Curr Pediatr Rev. 2025;21(2):192-199. doi: 10.2174/0115733963264010231213103328.
2
Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease.木香内酯减轻了胆汁淤积性肝病小鼠模型中DDC诱导的小胆管反应和炎症反应。
J Tradit Complement Med. 2023 Feb 27;13(4):345-357. doi: 10.1016/j.jtcme.2023.02.008. eCollection 2023 Jul.
3
Determination of Optimal Vitamin D Dosage in Children with Cholestasis.确定胆汁淤积症患儿的最佳维生素 D 剂量。
BMC Pediatr. 2023 Jun 21;23(1):313. doi: 10.1186/s12887-023-04113-y.

本文引用的文献

1
Exome Sequencing in Clinical Hepatology.外显子组测序在临床肝脏病学中的应用。
Hepatology. 2019 Dec;70(6):2185-2192. doi: 10.1002/hep.30826.
2
Obeticholic Acid: An Update of Its Pharmacological Activities in Liver Disorders.奥贝胆酸:其在肝脏疾病中药理活性的最新进展
Handb Exp Pharmacol. 2019;256:283-295. doi: 10.1007/164_2019_227.
3
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models.罗沙司他类似物挽救了细胞模型中内质网滞留的 ABCB4 变异体的细胞内运输和功能。
Sci Rep. 2019 Apr 30;9(1):6653. doi: 10.1038/s41598-019-43111-y.
4
Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study.原发性胆汁性胆管炎患者奥贝胆酸的长期疗效和安全性:一项国际开放标签扩展研究的 3 年结果。
Lancet Gastroenterol Hepatol. 2019 Jun;4(6):445-453. doi: 10.1016/S2468-1253(19)30094-9. Epub 2019 Mar 26.
5
Neonatal cholestasis: emerging molecular diagnostics and potential novel therapeutics.新生儿胆汁淤积症:新兴的分子诊断方法和潜在的新型治疗方法。
Nat Rev Gastroenterol Hepatol. 2019 Jun;16(6):346-360. doi: 10.1038/s41575-019-0132-z.
6
Universal screening of newborns for biliary atresia: Cost-effectiveness of alternative strategies.新生儿胆道闭锁的普遍筛查:替代策略的成本效益
J Med Screen. 2019 Sep;26(3):113-119. doi: 10.1177/0969141319832039. Epub 2019 Mar 14.
7
Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome.鉴定胆汁淤积性肝外胆管闭锁伴脾畸形综合征患儿多囊肾病 1 样 1 基因变异。
Hepatology. 2019 Sep;70(3):899-910. doi: 10.1002/hep.30515. Epub 2019 Mar 21.
8
The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis.非甾体法尼醇 X 受体激动剂西利福昔(GS-9674)可改善原发性硬化性胆管炎患者的胆汁淤积和肝损伤标志物。
Hepatology. 2019 Sep;70(3):788-801. doi: 10.1002/hep.30509. Epub 2019 Mar 10.
9
Cholic acid for primary bile acid synthesis defects: a life-saving therapy allowing a favorable outcome in adulthood.熊去氧胆酸治疗原发性胆汁酸合成缺陷:挽救生命的治疗方法,可使成年期获得良好结局。
Orphanet J Rare Dis. 2018 Oct 29;13(1):190. doi: 10.1186/s13023-018-0920-5.
10
ABCB4 Gene Aberrations in Human Liver Disease: An Evolving Spectrum.ABCB4 基因在人类肝脏疾病中的异常:一个不断演变的谱。
Semin Liver Dis. 2018 Nov;38(4):299-307. doi: 10.1055/s-0038-1667299. Epub 2018 Oct 24.