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复发性鼻咽鼻孢子虫病:卡塔尔的病例报告及文献综述

Recurrent nasopharyngeal rhinosporidiosis: Case report from Qatar and review of the literature.

作者信息

Ali Gawahir M, Goravey Wael, Al Hyassat Samir A, Petkar Mahir, Al Maslamani Muna A, Hadi Hamad Abdel

机构信息

Department of Infectious Diseases, Communicable Diseases Centre, Qatar.

Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Qatar.

出版信息

IDCases. 2020 Jul 3;21:e00901. doi: 10.1016/j.idcr.2020.e00901. eCollection 2020.

Abstract

Rhinosporidiosis is a chronic granulomatous infectious disease that predominantly affects the mucosal membranes of the nose and nasopharynx. The disease is caused by Rhinosporidium seeberi, an eukaryotic pathogen with distinct geographical distribution particularly in tropical and subtropical areas acquired mainly through aquatic exposure. We report a case of a young Nepalese male who presented with recurrent right nasopharyngeal mass where surgical excision and histopathological examination confirmed the diagnosis following distinct pathognomonic findings. There is no optimal effective management of the disease and surgical excision coupled with cauterization to prevent recurrence is the recommended best option since medical treatment alone is ineffective. The clinical presentation, assessment and management options are reviewed.

摘要

鼻孢子虫病是一种慢性肉芽肿性传染病,主要影响鼻和鼻咽的黏膜。该疾病由西伯鼻孢子菌引起,这是一种真核病原体,具有独特的地理分布,尤其在热带和亚热带地区,主要通过接触水而感染。我们报告一例年轻尼泊尔男性病例,该患者反复出现右鼻咽肿物,手术切除及组织病理学检查在发现明显的特征性表现后确诊。目前尚无针对该疾病的最佳有效治疗方法,由于单纯药物治疗无效,手术切除并烧灼以预防复发是推荐的最佳选择。本文对其临床表现、评估及治疗选择进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1347/7355714/7e97bc0d492b/gr1.jpg

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