《眼科医生、耳鼻喉科医生、心脏病专家、牙医、胃肠病学家、泌尿科医生、物理治疗师和精神科医生的帕金森病临床视角》。
Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists.
机构信息
Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
出版信息
J Korean Med Sci. 2020 Jul 20;35(28):e230. doi: 10.3346/jkms.2020.35.e230.
Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders. A range of NMS, particularly hyposmia, sleep disturbances, constipation, and depression, can even appear prior to the motor symptoms of PD. Because NMS can affect multiple organs and result in major disabilities, the recognition and multidisciplinary and collaborative management of NMS by physicians is essential for patients with PD. Therefore, the aim of this review article is to provide an overview of the organs that are affected by NMS in PD together with a brief review of pathophysiology and treatment options.
帕金森病（PD）是一种多系统疾病，除了运动功能障碍外，还伴有各种非运动症状（NMS）。NMS 包括睡眠、眼部、嗅觉、咽喉、心血管、胃肠道、泌尿生殖或肌肉骨骼等方面的障碍。一系列 NMS，尤其是嗅觉减退、睡眠障碍、便秘和抑郁，甚至可能在 PD 的运动症状之前出现。由于 NMS 可影响多个器官并导致严重残疾，因此，医生对 NMS 的识别和多学科协作管理对于 PD 患者至关重要。因此，本文综述的目的是概述 NMS 累及 PD 的器官，并简要综述其病理生理学和治疗选择。
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