Grisler R, Santeramo C, Scaricabarozzi R
Laboratorio di ricerche cliniche, anatomia ed istologia patologica, Istituti clinici di perfezionamento, Milano.
Quad Sclavo Diagn. 1988 Jan-Dec;24(1-4):213-8.
The simple Sclavo test based on succinyldicholine hydrolysis and on the following reaction with 5,5'-dithio-bis-2-nitrobenzoic acid for detection of the atypical patterns of serum cholinesterase has been investigated. A yellow staining appears but in presence of the atypical forms of the enzyme. Analysis of 4055 serum samples by the 430 Selective Analyzer Sclavo allowed the identification of one atypical homozygous patient. Prolonged apnoea induced by use of succinyldicholine as a neuromuscular blocking agent during anaesthesia may be avoided by use of this test.
