Gasior-Chrzan B
Przegl Dermatol. 1988 Nov-Dec;75(6):431-4.
External application of ovalbumin Lysozyme in normal saline in enzyme concentration 1 mg/ml shortened evidently the time of healing of standard skin wounds in guinea pigs (p less than 0.00001) as compared to control groups. The inflammatory reaction around the wound was reduced also. No manifestations of allergy to ovalbumin lysozyme were noted. This favourable effect of lysozyme on wound healing seems to be related to the cationic influence of lysozyme on cell membranes of keratinocytes and on change of wound pH.