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秘鲁香蕉皮(L.)对……的抗真菌活性:一项研究。 (注:原文中“on”后面内容缺失)

Antifungal Activity of Peruvian Banana Peel ( L.) on : An Study.

作者信息

Loyaga-Castillo Monica, Calla-Poma Roger D, Calla-Poma Rubén, Requena-Mendizabal Margarita F, Millones-Gómez Pablo A

机构信息

Department of Dentistry, Universidad Católica Los Ángeles de Chimbote, Perú.

Department of Oral Rehabilitation, Universidad Nacional Mayor de San Marcos, Perú.

出版信息

J Contemp Dent Pract. 2020 May 1;21(5):509-514.

Abstract

AIM

The purpose of this study was to compare the antifungal activity of three concentrations of a hydroethanolic extract of the × peel against strain ATCC 10231.

MATERIALS AND METHODS

The agar diffusion method was used, and the culture medium used was Sabouraud agar. Petri dishes were prepared with concentrations of 10, 30, and 50% of hydroethanolic extract of the × peel; nystatin was used as a positive control, and 96% ethanol was used as a negative control. After 24 hours of incubation, each plate was examined, and the diameters (mm) of the growth inhibition halos were measured around each well using a digital vernier caliper.

RESULTS

The results showed that the antifungal activity of the extract varied, depending on the concentration, as shown using analysis of variance (ANOVA; < 0.05). When comparing the different concentrations, it was found by Duncan test that the greatest activity was obtained at 50%.

CONCLUSION

It was concluded that the hydroethanolic extract of × at 50% exerted a greater antifungal effect on the strain of than did the extract at lower concentrations.

CLINICAL SIGNIFICANCE

By knowing the antimicrobial effect of × , this substance can be effectively used in products aimed to cure candidiasis infection.

摘要

目的

本研究旨在比较三种浓度的×果皮水乙醇提取物对ATCC 10231菌株的抗真菌活性。

材料与方法

采用琼脂扩散法,使用的培养基为沙保弱琼脂。制备含有10%、30%和50%×果皮水乙醇提取物的培养皿;制霉菌素用作阳性对照,96%乙醇用作阴性对照。孵育24小时后,检查每个平板,并用数字游标卡尺测量每个孔周围生长抑制圈的直径(mm)。

结果

结果表明,提取物的抗真菌活性因浓度而异,方差分析(ANOVA;<0.05)显示了这一点。比较不同浓度时,通过邓肯检验发现,50%浓度时活性最高。

结论

得出结论,50%的×水乙醇提取物对该菌株的抗真菌作用比低浓度提取物更强。

临床意义

通过了解×的抗菌作用,该物质可有效地用于旨在治疗念珠菌感染的产品中。

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