Third Department of Cardiology, Athens University School of Medicine, Athens, Greece.
Department of Pathophysiology, Athens University School of Medicine, Athens, Greece.
Curr Vasc Pharmacol. 2020;18(6):533-537. doi: 10.2174/1570161118666200721145718.
In Part 1 of this Thematic Issue entitled "Systemic Autoimmune Rheumatic Diseases and Cardiology", a panel of specialists and experts in cardiology, rheumatology, immunology and related fields discussed the cardiovascular complications of spondyloarthritides, rheumatoid arthritis, Sjogren's syndrome and vasculitides, as well as relevant cardiovascular issues related to non-biologic and biologic disease-modifying anti-rheumatic drugs (DMARDs), and provided their recommendations for prevention and management of these complications. In part 2 of this Thematic Issue, experts discuss the enhanced cardiovascular risk conferred by additional autoimmune rheumatic diseases (ARDs), including systemic lupus erythematosus, the antiphospholipid syndrome, psoriasis and psoriatic arthritis and juvenile idiopathic arthritis. These, and the previous articles, place inflammation as the key common link to explain the enhanced risk of cardiovascular complications in patients with ARDs. It follows that treatment should probably target inflammation. From all these contemporary reviews, the conclusion that is derived further supports the notion of the emerging field of Cardio- Rheumatology where physicians and experts from these two disciplines collaborate in risk stratification and optimization of preventive strategies and drug therapies in patients with ARDs.
在本期专题的第 1 部分“系统性自身免疫性风湿病与心脏病学”中,一组心脏病学、风湿病学、免疫学和相关领域的专家和学者讨论了脊柱关节炎、类风湿关节炎、干燥综合征和血管炎的心血管并发症,以及与非生物和生物疾病修饰抗风湿药物(DMARDs)相关的心血管问题,并就这些并发症的预防和管理提出了建议。在本期专题的第 2 部分,专家们讨论了其他自身免疫性风湿病(ARDs)带来的心血管风险增加,包括红斑狼疮、抗磷脂综合征、银屑病和银屑病关节炎以及青少年特发性关节炎。这些文章和之前的文章都将炎症作为解释 ARD 患者心血管并发症风险增加的关键共同联系。因此,治疗可能应该针对炎症。从所有这些当代综述中得出的结论进一步支持了心血管风湿病学这一新兴领域的观点,即这两个学科的医生和专家在 ARD 患者的风险分层和预防策略及药物治疗的优化方面进行合作。