Department of Functional Neurosurgery and Stereotaxy, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany,
Department of Functional Neurosurgery and Stereotaxy, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Prog Neurol Surg. 2020;35:105-115. doi: 10.1159/000509619. Epub 2020 Jul 21.
Neuropathic facial pain is notoriously difficult to treat, regardless of its origin and duration. Since the first reported sphenopalatine ganglion blockade by Sluder in 1908, this ganglion has assumed an important role among the structures targeted for the treatment of facial pain. Recent years have witnessed the rise of neuromodulation over ablative procedures, including the development of an implantable stimulation device specially designed for use in the pterygopalatine fossa. Sphenopalatine ganglion stimulation has been demonstrated as effective and safe for refractory cluster headache, today the major indication for this therapy, but increasing evidence shows that the effect on the autonomic system and cerebral circulation could justify an even wider use of sphenopalatine ganglion stimulation for other chronic headache syndromes and vascular diseases.
神经病理性面痛的治疗极具挑战性，无论其病因和病程如何。自 1908 年 Sluder 首次报道蝶腭神经节阻滞以来，该神经节在治疗面痛的目标结构中扮演着重要的角色。近年来，神经调节治疗的兴起已经超过了消融性手术，包括专门设计用于翼腭窝的可植入刺激装置的发展。蝶腭神经节刺激已被证明对难治性丛集性头痛有效且安全，这是目前该疗法的主要适应证，但越来越多的证据表明，其对自主神经系统和脑循环的影响可能证明蝶腭神经节刺激对其他慢性头痛综合征和血管疾病的更广泛应用是合理的。
