Curtis G D, Kraak W A, Mitchell R G
Bacteriology Department, John Radcliffe Hospital, Headington, Oxford.
J Clin Pathol. 1988 Dec;41(12):1331-3. doi: 10.1136/jcp.41.12.1331.
A latex agglutination test was compared with the micro-titration haemolysin inhibition method for the detection of anti-streptolysin O (ASO) antibodies in 428 serum samples. After slight modification of the latex method to produce maximal agglutination good agreement was shown between the results obtained by the two methods. The latex test had a sensitivity of 83.6%, a specificity of 93.3%, a predictive positive value of 86.5% and a predictive negative value of 91.6%. It was convenient, required less labour than the haemolysin test, and permitted economic testing of small numbers of sera.
对428份血清样本采用乳胶凝集试验与微量滴定溶血素抑制法检测抗链球菌溶血素O（ASO）抗体进行比较。对乳胶法进行轻微改进以产生最大凝集反应后，两种方法所得结果显示出良好的一致性。乳胶试验的灵敏度为83.6%，特异性为93.3%，阳性预测值为86.5%，阴性预测值为91.6%。该方法简便，比溶血素试验所需人力少，且允许对少量血清进行经济的检测。
