Department of Oral Surgery and Pathology, Faculty of Dentistry, Federal University of Minas Gerais, Minas Gerais, Brazil.
Department of Community and Preventive Dentistry, Faculty of Dentistry, Federal University of Minas Gerais, Minas Gerais, Brazil.
Minerva Stomatol. 2020 Dec;69(6):384-393. doi: 10.23736/S0026-4970.20.04389-7. Epub 2020 Jul 21.
Quantitative assessment of bleeding in dental extractions is rarely reported in the literature. The assessment of bleeding might provide additional evidence to predict and minimize postoperative outcomes. The aim of this study was to evaluate the pattern of bleeding in individuals taking direct oral anticoagulants (DOACs) submitted to dental extractions.
Intraoperative bleeding was evaluated by using total collected bleeding corrected by absorbance reading (dental bleeding score). To monitoring bleeding episodes from the day of surgery, this cohort was followed up until the seventh postoperative day.
Forty-five procedures were performed in three comparative groups, patients under DOACs, individuals taking vitamin K antagonists (VKAs) and without anticoagulant therapy. No bleeding events were observed in procedures carried out in individuals of the DOAC group. Additional hemostatic measures were required in two procedures in the VKA group and one in the non-anticoagulated group. The dental bleeding scores obtained for the DOAC and VKA groups were similar.
Our data suggest that the DOAC therapy did not result in increased bleeding outcomes in this sample.
在文献中很少有关于拔牙术中出血的定量评估。评估出血情况可能提供额外的证据，以预测和减少术后结果。本研究的目的是评估接受直接口服抗凝剂（DOACs）拔牙术的个体的出血模式。
通过使用总出血量校正的吸收读数（牙科出血评分）来评估术中出血。为了监测手术当天的出血事件，该队列在术后第 7 天进行了随访。
在 DOACs 组、服用维生素 K 拮抗剂（VKAs）的个体和未接受抗凝治疗的个体的三个对比组中进行了 45 例手术。在 DOAC 组的手术中未观察到出血事件。在 VKA 组中有两例手术和非抗凝组中有一例手术需要额外的止血措施。DOAC 和 VKA 组获得的牙科出血评分相似。
我们的数据表明，在本样本中，DOAC 治疗并未导致出血结果增加。
