Dermatology and Venereology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Ophthalmology, Departments, Faculty of Medicine, Tanta University, Tanta, Egypt.
J Dermatolog Treat. 2022 Mar;33(2):1017-1022. doi: 10.1080/09546634.2020.1800569. Epub 2020 Jul 29.
Dermatochalasis is frequently associated with tissue ageing and leads to multiple functional and cosmetic issues. There are several possible medical and surgical treatments available, such as blepharoplasty and laser therapy.
The aim of this work was to evaluate plasma exeresis as a new technique for nonsurgical treatment of dermatochalasis of the upper eyelid.
This clinical trial included 40 female patients with dermatochalasis. Each patient received 3 sessions of treatment with the technology of plasma exeresis with one-month interval. Final evaluation was performed three months after the last session by 2 blinded dermatologists and 2 ophthalmologists, lid laxity according to facial laxity rating scale (FLRS), marginal crease distance (MCD) before and after treatment and patient satisfaction score.
There was a significant decrease in eye lid laxity (FLRS) after treatment where < .001; 36 (90%) patients had change and 4 (10%) patients without change in general. There was a significant increase in MCD after treatment ( = .001).
Plasma exeresis seems to improve appearance of the upper eyelid, without any serious adverse events and could be a valid solution for dermatochalasis especially in mild and moderate cases.
皮肤松弛症常与组织老化有关，并导致多种功能和美容问题。有几种可能的医学和手术治疗方法，如眼睑成形术和激光治疗。
本研究旨在评估等离子切除术作为一种治疗上眼睑皮肤松弛症的非手术新技术。
本临床试验纳入了 40 名女性皮肤松弛症患者。每位患者接受了 3 次等离子切除术治疗，间隔 1 个月。末次治疗后 3 个月，由 2 名盲法皮肤科医生和 2 名眼科医生进行最终评估，根据面部松弛评分量表（FLRS）评估眼睑松弛度、治疗前后的睑缘褶皱距离（MCD）和患者满意度评分。
治疗后眼睑松弛度（FLRS）显著下降（ < .001）；36 例（90%）患者有变化，4 例（10%）患者无变化。治疗后 MCD 显著增加（ = .001）。
等离子切除术似乎可以改善上眼睑的外观，且无严重不良事件，对于皮肤松弛症，特别是轻度和中度病例，是一种有效的解决方案。
