Neonatal Intensive Care Unit, Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.
Faculty of Medicine, Oporto University, Porto, Portugal.
J Matern Fetal Neonatal Med. 2022 Aug;35(15):2961-2964. doi: 10.1080/14767058.2020.1786526. Epub 2020 Jul 23.
Over the past 4 months, SARS-CoV-2 pandemic has spread all over the world. The lack of understanding of this pandemic epidemiological characteristics, clinical implications and long term consequences have raised concern among healthcare workers. Pregnant women and newborns are a particularly worrisome population since data referring to real infection impact in these patients are scarce and management controversial. We report on the perinatal management of the first consecutive ten mother-infant dyads of SARS-CoV-2 infection complicated pregnancy. All mothers were included in newborn management planning prior to delivery and decided on separation from their newborns; nine decided on postponing breastfeeding until SARS-CoV-2 negativity while maintaining lactation stimulation. No evidence of vertical transmission was found (all NP swab and bronchial secretions SARS-CoV-2 RT-PCR were negative). No newborn developed clinical evidence of infection. In the face of current scientific uncertainty, decisions of perinatal management, such as mother-infant separation and breastfeeding, must involve parents in a process of shared decision making.
在过去的 4 个月中，SARS-CoV-2 大流行已在全球范围内蔓延。由于缺乏对这种大流行病的流行病学特征、临床意义和长期后果的了解，医护人员对此感到担忧。孕妇和新生儿是一个特别令人担忧的群体，因为关于这些患者实际感染影响的数据很少，且管理存在争议。我们报告了首例连续 10 对 SARS-CoV-2 感染合并妊娠的母婴对的围产期管理情况。所有母亲在分娩前都被纳入新生儿管理计划，并决定与新生儿分开；9 位母亲决定推迟母乳喂养，直到 SARS-CoV-2 转为阴性，同时保持泌乳刺激。未发现垂直传播的证据（所有 NP 拭子和支气管分泌物的 SARS-CoV-2 RT-PCR 均为阴性）。没有新生儿出现感染的临床证据。面对当前的科学不确定性，母婴分离和母乳喂养等围产期管理决策必须让父母参与共同决策过程。
