Opinion: It's ethical to test promising coronavirus vaccines against less-promising ones.
作者信息
Eyal Nir, Lipsitch Marc
机构信息
Center for Population-Level Bioethics and Department of Philosophy, Rutgers University, New Brunswick, NJ 08901;
Department of Health Behavior, Society, and Policy, Rutgers School of Public Health, Piscataway, NJ 08854.
出版信息
Proc Natl Acad Sci U S A. 2020 Aug 11;117(32):18898-18901. doi: 10.1073/pnas.2014154117. Epub 2020 Jul 22.
Abstract
摘要
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本文引用的文献
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Ethical considerations for epidemic vaccine trials.传染病疫苗试验的伦理考量。
J Med Ethics. 2020 Jul;46(7):465-469. doi: 10.1136/medethics-2020-106235. Epub 2020 May 15.
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Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure.人类挑战研究加速冠状病毒疫苗许可。
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Research ethics for emerging trial designs: does equipoise need to adapt?新型试验设计的研究伦理：均衡性是否需要调整？
BMJ. 2018 Jan 25;360:k226. doi: 10.1136/bmj.k226.
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J Med Ethics. 2018 Jun;44(6):409-415. doi: 10.1136/medethics-2017-104549. Epub 2017 Nov 24.
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Combating Emerging Threats--Accelerating the Availability of Medical Therapies.应对新出现的威胁——加快医学疗法的可及性。
N Engl J Med. 2015 Sep 10;373(11):993-5. doi: 10.1056/NEJMp1508708. Epub 2015 Aug 5.
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