Mener Amanda, Runner Robert P, Michael Keith W, Boden Scott D
Emory University School of Medicine, Atlanta, Georgia.
Department of Orthopaedics, Emory University, Atlanta, Georgia.
Int J Spine Surg. 2020 Jun 30;14(3):403-411. doi: 10.14444/7053. eCollection 2020 Jun.
Previous studies stratified postoperative infection risk by patient comorbidities. However, it is unclear whether the incidence varies by surgical approach in a specialized orthopaedic setting. This study aims to compare infection rates and microbiologic characteristics of postoperative spine infections requiring return to the operating room for debridement by hospital setting: a dedicated orthopaedic and spine hospital versus a general hospital serving multiple surgical specialties.
The study is a retrospective review of prospectively collected data. Procedures performed between March 2006 and August 2008 at the multispecialty university hospital were compared with cases at an orthopaedic specialty hospital from September 2008 through August 2016. The surgeons, residents, and patients were similar, but the operative venue changed in 2008.
The overall general university hospital infection rate was 2.03%, higher than the overall infection rate at the dedicated orthopaedic and spine hospital of 1.31% ( < .0104). The general university infection rate was 2.27% in the final years of practice, compared with 0.91% at the dedicated orthopaedic and spine hospital ( < .0001) during a recent 2-year time frame. Demographic variables did not significantly differ between the 2 settings. The overall proportion of Gram-negative infection rates was not statistically different (21.7% vs 18.6%), despite an increased proportion of Gram-negative infections at the general university hospital following surgery from an anterior approach. Most of the organisms isolated in both facilities were species. There was no difference in the seasonality of postoperative spine infections in either setting.
In transitioning from a multispecialty university hospital to a dedicated orthopaedic hospital, the incidence of postoperative spine infections was significantly reduced to 0.91%. Despite the change in venue, the proportion of Gram-negative infections (∼20%) following spine surgery did not significantly change. These results suggest improved infection rates during the course of the last 10 years with consistent proportions of Gram-negative infections.
既往研究根据患者合并症对术后感染风险进行分层。然而,在专业骨科环境中,感染发生率是否因手术方式而异尚不清楚。本研究旨在比较因术后脊柱感染需要返回手术室进行清创的患者的感染率和微生物学特征,比较的医院环境为:一家专门的骨科和脊柱医院与一家服务多个外科专业的综合医院。
本研究是对前瞻性收集的数据进行回顾性分析。将2006年3月至2008年8月在多专业大学医院进行的手术与2008年9月至2016年8月在一家骨科专科医院的病例进行比较。外科医生、住院医师和患者相似,但手术地点在2008年发生了变化。
综合大学医院的总体感染率为2.03%,高于专门的骨科和脊柱医院的总体感染率1.31%(P<0.0104)。在最近2年的时间框架内,综合大学医院在最后几年的感染率为2.27%,而专门的骨科和脊柱医院为0.91%(P<0.0001)。两种环境下的人口统计学变量无显著差异。革兰氏阴性菌感染率的总体比例无统计学差异(21.7%对18.6%),尽管综合大学医院前路手术后革兰氏阴性菌感染比例有所增加。两家机构分离出的大多数微生物均为 菌种。两种环境下术后脊柱感染的季节性均无差异。
从多专业大学医院转变为专门的骨科医院后,术后脊柱感染的发生率显著降低至0.91%。尽管手术地点发生了变化,但脊柱手术后革兰氏阴性菌感染的比例(约20%)没有显著变化。这些结果表明,在过去10年中感染率有所改善,革兰氏阴性菌感染比例保持一致。
3级。