Philosophisch-Theologische Hochschule Vallendar, Vallendar, Germany.
Bioethics. 2021 Jan;35(1):72-78. doi: 10.1111/bioe.12787. Epub 2020 Jul 23.
Recent developments in generating gametes via in vitro gametogenesis (IVG) from induced pluripotent stem cells (iPSCs) and their successful use for reproductive purposes in animals strongly suggest that soon these methods could also be used in human reproduction. At least two questions emerge in this context: (a) if a legislator should permit their use and (b) if ethical claims emerge that support their provision, e.g., by public health care systems. This urges an ethical reflection of the new reproductive options this technique might offer. Since the concept of reproductive freedom is a key aspect for the ethical evaluation of artificial reproductive technologies (ARTs), it is necessary to analyze if the new possibilities emerging from IVG fall within the scope of this concept. The results may constitute a morally relevant difference between different imaginable applications of IVG and potentially justify differences in claims to access this technology.
最近，通过体外配子发生（IVG）从诱导多能干细胞（iPSCs）中产生配子的技术取得了进展，并且这些技术在动物的生殖目的上取得了成功，这强烈表明这些方法很快也可以用于人类生殖。在此背景下，至少出现了两个问题：(a)立法者是否应该允许使用这些方法，以及(b)是否出现了支持提供这些方法的伦理主张，例如通过公共医疗保健系统。这就迫切需要对这项技术可能提供的新生殖选择进行伦理反思。由于生殖自由的概念是人工生殖技术（ART）伦理评估的一个关键方面，因此有必要分析 IVG 带来的新可能性是否属于这一概念的范畴。这些结果可能构成不同想象的 IVG 应用之间具有道德相关性的差异，并可能为对获取这项技术的主张进行区分提供依据。
