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[斜外侧腰椎椎间融合术后脊柱-骨盆矢状面参数改变与临床疗效的关系]

[Relationship between alterations of spine-pelvic sagittal parameters and clinical outcomes after oblique lumbar interbody fusion].

作者信息

Sun Xiu-Min, Xu Hong-Guang, Xiao Liang, Liu Chen, Yang Xiao-Ming, Zhao Quan-Lai, Nie Wen-Lei

机构信息

Spine Surgery Research Center of Wannan Medical College, Department of Spine Surgery, Yijishan Hospital, the First Affiliated Hospital of Wannan Medical College, Wuhu 241001, Anhui, China.

出版信息

Zhongguo Gu Shang. 2020 Jul 25;33(7):609-14. doi: 10.12200/j.issn.1003-0034.2020.07.004.

Abstract

OBJECTIVE

To investigate the relationship between spine-pelvic sagittal parameters and clinical efficacy before and after oblique lumbar interbody fusion(OLIF).

METHODS

A retrospective analysis of clinical data of 65 patients with lumbar degenerative diseases treated with OLIF were performed from July 2017 to July 2018. There were 26 males and 39 females aged from 33 to 79 years old with an average of (62.72±10.23) years old. Oswestry Disability Index (ODI) and visual analogue scale (VAS) before and at the latest follow up were evaluated. Disc height (DH) and spine- pelvic sagittal parameters of the surgical segment were measured before and at the latest follow- up, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS) and lumbar lordosis (LL). According to the difference of PI-LL, it was judged whether PI and LL match and the patients were grouped, PI-LL ranged from -9° to 9° was set as matching group, and PI-LL less than -9° or larger than 9° was set as mismatching group. The spine-pelvic sagittal parameters were analyzed before and at the latest follow-up of OLIF in patients with lumbar degenerative diseases, and the correlation between changes and clinical efficacy was compared.

RESULTS

All patients were followed up from 8 to 20 months with an average of (14.20±3.68) months. Operation time was (91.54±25.97) min, intraoperative blood loss was (48.15±10.14) ml, and the hospitalization time ranged from 6 to 19 days with an average of (9.28± 2.50) days. Totally 84 surgical levels, 46 patients were single segment and 19 patients were double segments. VAS and ODI score were improved from (4.88±0.99) point, (67.60±13.73) % preoperatively to (2.85±1.30) points, (30.57±6.48) % at the latest follow-up. There were significant differences in VAS and ODI scores between before and at the latest follow-up. The sagittal parameters of LL, PT, SS, PI, PI -LL and the surgical level DH were (42.80 ±16.35)° , (23.22 ±10.91)° , (26.95 ± 13.30)°, (50.22±14.51)°, (7.53±16.13) °, (0.91±0.29) cm preoperatively and improved to the latest follow-up (49.95± 12.82) °, (17.94±9.24) °, (33.71±12.66) °, (51.65±10.26) °, (1.68±17.00) °, (1.20±0.40) cm;there were statistical differences in LL, PT, SS, PI-LL, DH before operation and at the latest follow up, while no difference in PI. LL of preoperative PI-LL in matched group was (48.76±11.09)° , and (38.00±18.37)° in PI-LL mismatch group, there was difference between two groups. There were no differences in VAS, ODI, PT, SS, PI and DH between two groups. At the latest follow-up, ODI between PI-LL matched group and PI-LL mismatched group were (29.40±5.93)% and (32.86±7.02)% respectively, and had difference in ODI between two groups;while there were no significant differences in VAS, LL, PT, SS, PI, and DH. Pearson correlation analysis showed preoperative PT-LL was positively correlated with VAS;PT was positively correlated with ODI at the latest follow-up.

CONCLUSION

OLIF has a good surgical effect on lumbar degenerative diseases, and could change spine-pelvic sagittal parameters of patient to a certain extent, and further restoring the balance of the sagittal plane of lumbar spine.

摘要

目的

探讨斜外侧腰椎椎间融合术(OLIF)前后脊柱-骨盆矢状面参数与临床疗效的关系。

方法

回顾性分析2017年7月至2018年7月采用OLIF治疗的65例腰椎退行性疾病患者的临床资料。其中男性26例,女性39例,年龄33~79岁,平均(62.72±10.23)岁。评估术前及末次随访时的Oswestry功能障碍指数(ODI)和视觉模拟评分(VAS)。测量手术节段术前及末次随访时的椎间盘高度(DH)和脊柱-骨盆矢状面参数,包括骨盆入射角(PI)、骨盆倾斜角(PT)、骶骨倾斜角(SS)和腰椎前凸角(LL)。根据PI-LL的差值判断PI与LL是否匹配并进行分组,将PI-LL范围在-9°至9°设定为匹配组,PI-LL小于-9°或大于9°设定为不匹配组。分析腰椎退行性疾病患者OLIF术前及末次随访时的脊柱-骨盆矢状面参数,并比较其变化与临床疗效的相关性。

结果

所有患者随访8~20个月,平均(14.20±3.68)个月。手术时间为(91.54±25.97)分钟,术中出血量为(48.15±10.14)毫升,住院时间6~19天,平均(9.28±2.50)天。共84个手术节段,46例为单节段,19例为双节段。VAS和ODI评分从术前的(4.88±- 0.99)分、(67.60±13.73)%改善至末次随访时的(2.85±1.30)分、(30.57±6.48)%。术前与末次随访时VAS和ODI评分差异有统计学意义。LL、PT、SS、PI、PI-LL矢状面参数及手术节段DH术前分别为(42.80±16.35)°、(23.22±10.91)°、(26.95±13.30)°℃、(50.22±14.51)°、(7.53±16.13)°、(0.91±0.29)厘米,至末次随访时改善为(49.95±12.82)°、(17.94±9.24)°、(33.71±12.66)°、(51.65±10.26)°、(1.68±17.00)°、(1.20±0.40)厘米;术前与末次随访时LL、PT、SS、PI-LL、DH差异有统计学意义,而PI无差异。匹配组术前PI-LL的LL为(48.76±11.09)°,PI-LL不匹配组为(38.00±18.37)°,两组间有差异。两组间VAS、ODI、PT、SS、PI和DH无差异。末次随访时,PI-LL匹配组与PI-LL不匹配组的ODI分别为(29.40±5.93)%和(32.86±7.02)%,两组间ODI有差异;而VAS、LL、PT、SS、PI和DH无显著差异。Pearson相关性分析显示术前PT-LL与VAS呈正相关;末次随访时PT与ODI呈正相关。

结论

OLIF治疗腰椎退行性疾病手术效果良好,能在一定程度上改变患者脊柱-骨盆矢状面参数,进一步恢复腰椎矢状面平衡。

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