Clinical Epidemiology Division, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Slone Epidemiology Center at Boston University.
Curr Opin Pulm Med. 2020 Sep;26(5):527-534. doi: 10.1097/MCP.0000000000000715.
The aim of this review is to describe the latest studies on sarcoidosis incidence, prevalence and risk factors with a special focus on reports in the last 2 years. The potential biases affecting these studies are discussed.
The prevalence and incidence of sarcoidosis vary greatly depending on region of the world. Variations in data sources and settings can affect estimates of the burden of sarcoidosis, sometimes making them difficult to compare across countries. It is not well understood how the distribution of sarcoidosis phenotypes differs across populations. Age, sex and race are the most important sources of variation in incidence and prevalence. Recent epidemiological studies provide new insights on the role of genetic and nongenetic risk factors for sarcoidosis.
High-quality and systematically collected data, with depth (detailed information per individual) and breadth (many individuals), is needed to further understand the complexity and heterogeneity of sarcoidosis.
本综述旨在描述最近关于结节病发病率、患病率和危险因素的研究，特别关注过去 2 年的报告。讨论了这些研究中可能存在的潜在偏倚。
结节病的患病率和发病率因世界不同地区而有很大差异。数据来源和环境的差异会影响结节病负担的估计，有时使得各国之间的比较变得困难。结节病表型的分布在不同人群中如何不同尚不清楚。年龄、性别和种族是发病率和患病率变化的最重要来源。最近的流行病学研究提供了有关结节病遗传和非遗传危险因素作用的新见解。
需要高质量、系统收集的数据，具有深度（个体的详细信息）和广度（许多个体），以进一步了解结节病的复杂性和异质性。
