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68Ga-前列腺特异性膜抗原-11 摄取的心脏转移灶在腺样囊性癌患者中的表现,一种罕见癌症的罕见表现。

68Ga-Prostate-Specific Membrane Antigen-11-Avid Cardiac Metastases in a Patient With Adenoid Cystic Carcinoma, A Rare Presentation of a Rare Cancer.

机构信息

From the Department of Medical Oncology, Radboud Institute for Health Sciences.

Department of Radiology, Nuclear Medicine and Anatomy, Radboud University Medical Center, Nijmegen, the Netherlands.

出版信息

Clin Nucl Med. 2020 Sep;45(9):716-718. doi: 10.1097/RLU.0000000000003204.

Abstract

Adenoid cystic carcinoma is a rare cancer that arises from secretory glands. Metastases are mainly seen in the lungs and bones. Cardiac metastases are extremely rare; only 1 case has previously been described. In this patient, cardiac metastases were suspected based on CT imaging. Tumor imaging by Ga-prostate-specific membrane antigen (PSMA)-11 PET is mainly used in prostate cancer patients but is also of interest in adenoid cystic carcinoma patients because of high PSMA-ligand uptake in salivary glands. Ga-PSMA-11 PET imaging supported the suspicion of cardiac metastases, because the cardiac lesions showed similar tracer uptake compared with other metastases.

摘要

腺样囊性癌是一种罕见的癌症,起源于分泌腺。转移主要见于肺部和骨骼。心脏转移极为罕见,此前仅描述过 1 例。在该患者中,基于 CT 影像学,怀疑存在心脏转移。Ga-前列腺特异性膜抗原(PSMA)-11 PET 肿瘤成像主要用于前列腺癌患者,但在腺样囊性癌患者中也很有意义,因为唾液腺对 PSMA 配体摄取较高。Ga-PSMA-11 PET 成像支持心脏转移的怀疑,因为心脏病变与其他转移灶相比,显示出类似的示踪剂摄取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/903f/7409769/ecd383d74d00/rlu-45-716-g001.jpg

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