From the Department of Medical Oncology, Radboud Institute for Health Sciences.
Department of Radiology, Nuclear Medicine and Anatomy, Radboud University Medical Center, Nijmegen, the Netherlands.
Clin Nucl Med. 2020 Sep;45(9):716-718. doi: 10.1097/RLU.0000000000003204.
Adenoid cystic carcinoma is a rare cancer that arises from secretory glands. Metastases are mainly seen in the lungs and bones. Cardiac metastases are extremely rare; only 1 case has previously been described. In this patient, cardiac metastases were suspected based on CT imaging. Tumor imaging by Ga-prostate-specific membrane antigen (PSMA)-11 PET is mainly used in prostate cancer patients but is also of interest in adenoid cystic carcinoma patients because of high PSMA-ligand uptake in salivary glands. Ga-PSMA-11 PET imaging supported the suspicion of cardiac metastases, because the cardiac lesions showed similar tracer uptake compared with other metastases.
腺样囊性癌是一种罕见的癌症,起源于分泌腺。转移主要见于肺部和骨骼。心脏转移极为罕见,此前仅描述过 1 例。在该患者中,基于 CT 影像学,怀疑存在心脏转移。Ga-前列腺特异性膜抗原(PSMA)-11 PET 肿瘤成像主要用于前列腺癌患者,但在腺样囊性癌患者中也很有意义,因为唾液腺对 PSMA 配体摄取较高。Ga-PSMA-11 PET 成像支持心脏转移的怀疑,因为心脏病变与其他转移灶相比,显示出类似的示踪剂摄取。