Getting It Right First Time Programme, NHS England and NHS Improvement, London, UK.
Getting It Right First Time Programme, NHS England and NHS Improvement, London, UK; Royal National Orthopaedic Hospital, Stanmore, London, UK.
J Arthroplasty. 2020 Dec;35(12):3631-3637. doi: 10.1016/j.arth.2020.06.081. Epub 2020 Jul 2.
We aimed to understand the role of fixation method in predicting subsequent revision rates in people aged 70 years and older undergoing elective primary total hip arthroplasty (THA) within the UK National Health Service (NHS).
Data on elective primary THAs conducted in people aged 70 years and older between April 1, 2012, and March 31, 2018, and subsequent revisions conducted up to March 31, 2019, were extracted from the Hospital Episodes Statistics database for all NHS procedures in England. A flexible parametric competing risks model was used to identify the role of fixation method in predicting revision and adjust for age, sex, frailty, year of surgery, and all-cause mortality.
Data were available for 190,656 procedures. Crude revision rates at 1-7 years follow-up in those who had cemented, hybrid/reverse hybrid, and uncemented fixation were 1.8%, 1.8%, and 2.3%, respectively. There was a high level of variation between NHS trusts in the proportionate use of fixation method. The differences in the hazard of revision between uncemented and cemented fixation (hazard ratio, 1.238 [95% confidence interval, 1.148-1.336]) and hybrid/reverse hybrid fixation (hazard ratio, 1.184 [95% confidence interval, 1.082-1.297]) were both significant. In secondary analysis, there was evidence that revision rates in trusts where uncemented fixation predominated were not significantly lower for uncemented fixation compared to all other fixation methods.
Revision rates were significantly higher for elective primary THA in people aged 70 years and older who have uncemented fixation, compared to those who had cemented and hybrid/reverse hybrid fixation.
我们旨在了解在英国国民保健制度(NHS)中,70 岁及以上人群行择期初次全髋关节置换术(THA)时固定方法对预测后续翻修率的作用。
从英格兰 NHS 所有手术的医院病例统计数据库中提取了 2012 年 4 月 1 日至 2018 年 3 月 31 日期间行择期初次 THA 且至 2019 年 3 月 31 日前行后续翻修术的 70 岁及以上人群的数据。采用灵活参数竞争风险模型来确定固定方法在预测翻修中的作用,并调整年龄、性别、脆弱性、手术年份和全因死亡率。
共纳入 190656 例手术。在 1-7 年的随访中,骨水泥固定、混合/反向混合固定和非骨水泥固定的翻修率分别为 1.8%、1.8%和 2.3%。NHS 信托机构之间固定方法的使用比例差异很大。非骨水泥固定与骨水泥固定(危险比,1.238[95%置信区间,1.148-1.336])和混合/反向混合固定(危险比,1.184[95%置信区间,1.082-1.297])的翻修风险差异均有统计学意义。在二次分析中,有证据表明,在非骨水泥固定占主导地位的信托机构中,与所有其他固定方法相比,非骨水泥固定的翻修率并没有显著降低。
与骨水泥固定和混合/反向混合固定相比,70 岁及以上行择期初次 THA 的人群中非骨水泥固定的翻修率显著更高。