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退伍军人选择计划与退伍军人事务部医疗保健系统治疗丙型肝炎的疗效比较。

Outcomes Comparison of the Veterans' Choice Program With the Veterans Affairs Health Care System for Hepatitis C Treatment.

作者信息

Chao Daniel, Buddha Hema, Damodaran Chitra, Tran Linda, Strong Richard, Jackson Christian S

机构信息

, and are Physicians; and is a Pharmacist; all in the Gastroenterology Section at VA Loma Linda Healthcare System in California. is a Clinical Research Program Administrator at the University of California, Riverside. Daniel Chao, Chitra Damodaran, and Christian Jackson are Assistant Professors of Medicine and Richard Strong is an Associate Professor of Medicine, at Loma Linda University in California.

出版信息

Fed Pract. 2020 Jun;37(Suppl 3):S18-S24.

Abstract

BACKGROUND

The US Department of Veterans Affairs (VA) has been stressed by the large number of veterans requiring direct-acting antiviral (DAA) medications for hepatitis C virus (HCV) treatment. The Veterans Choice Program provides VA patients more options to receive treatment. This study compared the experience of veterans who received HCV treatment through the Veterans Choice Program and those that received treatment at the VA Loma Linda Healthcare System (VALLHCS) in fiscal year (FY) 2016.

METHODS

A chart review was performed on all veterans referred by VALLHCS to Choice for HCV treatment during FY 2016, and matched to veterans who received treatment at VALLHCS. Data collected included Fibrosis-4 score (Fib-4), platelet count, days elapsed between time of referral and time of appointment (wait time), rate of sustained virologic response at 12 weeks (SVR12), reason for treatment failure, and cost effectiveness.

RESULTS

One hundred veterans were referred to Choice; 71 were seen at least once by a Choice provider, and 61 completed a treatment course. Mean Fib-4 and platelet count was 1.9 and 228,000 for the Choice population and 3.4 and 158,000 for the VALLHCS population, respectively. There was no difference in SVR12 rate. Mean wait time was 42 days for Choice vs 29 days for VALLHCS ( < .001). Choice health care providers incurred a mean $8,561.40 in additional costs per veteran seen.

CONCLUSIONS

While treatment success rates were similar between Choice and VALLHCS, the degree of liver fibrosis was more advanced in the VALLHCS population. The wait time for care was longer with Choice compared with a direct referral within the VA. While Choice offers a potential solution to providing care for veterans, the current program has unique problems that must be considered.

摘要

背景

美国退伍军人事务部(VA)因大量退伍军人需要使用直接抗病毒(DAA)药物治疗丙型肝炎病毒(HCV)而不堪重负。退伍军人选择计划为VA患者提供了更多接受治疗的选择。本研究比较了2016财年通过退伍军人选择计划接受HCV治疗的退伍军人与在VA洛马琳达医疗保健系统(VALLHCS)接受治疗的退伍军人的经历。

方法

对2016财年VALLHCS转介至选择计划接受HCV治疗的所有退伍军人进行病历审查,并与在VALLHCS接受治疗的退伍军人进行匹配。收集的数据包括Fibrosis-4评分(Fib-4)、血小板计数、转诊时间与预约时间之间的天数(等待时间)、12周持续病毒学应答率(SVR12)、治疗失败原因和成本效益。

结果

100名退伍军人被转介至选择计划;71名至少接受过一次选择计划提供者的诊治,61名完成了一个疗程的治疗。选择计划人群的平均Fib-4和血小板计数分别为1.9和228,000,VALLHCS人群分别为3.4和158,00o。SVR12率无差异。选择计划的平均等待时间为42天,而VALLHCS为29天(P<0.001)。选择计划的医疗保健提供者诊治的每位退伍军人平均额外花费8,561.40美元。

结论

虽然选择计划和VALLHCS的治疗成功率相似,但VALLHCS人群的肝纤维化程度更严重。与在VA内直接转诊相比,选择计划的护理等待时间更长。虽然选择计划为退伍军人提供护理提供了一个潜在的解决方案,但当前的计划有一些必须考虑的独特问题。

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本文引用的文献

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Ann Hepatol. 2019 Mar-Apr;18(2):304-309. doi: 10.1016/j.aohep.2018.06.001. Epub 2019 Apr 12.
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Platelet count and sustained virological response in hepatitis C treatment.
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Epidemiology of hepatitis C virus infection in American veterans.
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